سعر لاناكلور 250 مجم /5مل معلق 60 مل 2024

Cefaclor 250 mg/5 mL oral suspension, 60 mL bottle, by Chemipharm (Egypt); second-generation oral cephalosporin antibiotic.

• Otitis media caused by susceptible S. pneumoniae, H. influenzae, staphylococci and S. pyogenes.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Lower respiratory tract infections, including pneumonia, caused by susceptible S. pneumoniae, H. influenzae and S. pyogenes.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Pharyngitis and tonsillitis caused by S. pyogenes (penicillin is the usual drug of choice).Population: Adults and childrenDailyMed (U.S. National Library of Medicine)

• Hypersensitivity reactions in about 1.5% of patients (morbilliform eruptions about 1 in 100; pruritus, urticaria and positive Coombs tests each fewer than 1 in 200); serum-sickness-like reactions (erythema multiforme, rash, arthritis/arthralgia with or without fever) have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Gastrointestinal symptoms in about 2.5% of patients, including diarrhoea (about 1 in 70).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known allergy to the cephalosporin group of antibiotics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Before therapy, ask about previous hypersensitivity to cefaclor, cephalosporins, penicillins or other drugs; cross-hypersensitivity among beta-lactams may occur in up to 10% of penicillin-allergic patients. Stop the drug if an allergic reaction occurs; serious reactions may need epinephrine and emergency measures.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pseudomembranous colitis (Clostridioides difficile) has been reported, ranging from mild to life-threatening; consider it in patients with diarrhoea after antibiotic use.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prolonged use may cause overgrowth of non-susceptible organisms; positive direct Coombs tests have been reported; prescribe with caution in patients with a history of gastrointestinal disease, particularly colitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• ProbenecidProbenecid inhibits the renal excretion of cefaclor.DailyMed (U.S. National Library of Medicine)
• Oral anticoagulantsIncreased anticoagulant effect has been reported when cefaclor and oral anticoagulants were given together.DailyMed (U.S. National Library of Medicine)
• Urine glucose tests (Benedict, Fehling, Clinitest)May give a false-positive reaction for glucose in the urine with copper-reduction tests.DailyMed (U.S. National Library of Medicine)

• Reproduction studies in mice, rats and ferrets showed no fetal harm, but there are no adequate and well-controlled studies in pregnant women; use in pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Small amounts of cefaclor are found in breast milk after a single 500 mg dose (about 0.16-0.21 mcg/mL at 2-5 hours); the effect on the nursing infant is unknown, so use with caution.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefaclor: Bactericidal; like other cephalosporins it inhibits bacterial cell-wall synthesis. Inactive against methicillin-resistant staphylococci.