سعر لوزابرس-اتش 50/12.5مجم 7 قرص 2026

Lozapress-h 50/12.5mg 7 tablets (Egypt; Sigma): tablets combining losartan potassium 50 mg (angiotensin II receptor blocker) and hydrochlorothiazide 12.5 mg (thiazide diuretic) for hypertension.

• Treatment of hypertension, to lower blood pressure and reduce the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy (evidence suggests this benefit does not apply to Black patients).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component; anuria; coadministration with aliskiren in patients with diabetes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fetal toxicity - discontinue as soon as possible when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Hypotension in volume- or salt-depleted patients; impaired renal function; hypersensitivity; electrolyte and metabolic effects (hypokalemia, hyponatremia, hyperuricemia/gout, hyperglycemia, lipid increases); acute myopia and secondary angle-closure glaucoma (hydrochlorothiazide); exacerbation of systemic lupus erythematosus.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Agents increasing serum potassiumMay increase serum potassium; monitor.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay deteriorate renal function and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)

• Drugs acting on the renin-angiotensin system during the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as possible when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Thiazides appear in human milk; unknown whether losartan is excreted in human milk; decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Losartan potassium: Selectively blocks binding of angiotensin II to the AT1 receptor (losartan and its active metabolite).
• Hydrochlorothiazide: Thiazide diuretic acting on renal tubular electrolyte reabsorption, increasing sodium and chloride excretion.