سعر ليرولين 50مجم 30 كبسولة 2026

Lyrolin 50 mg pregabalin oral capsules, pack of 30, by Hikma Pharma (Egypt).

• Neuropathic pain associated with diabetic peripheral neuropathy.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Postherpetic neuralgia.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizures.Population: Patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)

• Most common (at least 5% and twice placebo): dizziness, somnolence, dry mouth, oedema, blurred vision, weight gain and abnormal thinking (mainly difficulty concentrating).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any component of the product.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema (swelling of face, mouth, throat) and other hypersensitivity reactions: stop immediately; use caution with previous angioedema or with other drugs causing angioedema such as ACE inhibitors.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs including pregabalin increase the risk of suicidal thoughts or behaviour; monitor for new or worsening depression or unusual mood changes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serious, sometimes fatal respiratory depression can occur with opioids or other CNS depressants or with underlying respiratory impairment; start at a low dose and monitor.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Opioids and other CNS depressants (e.g. benzodiazepines, alcohol)Additive sedation and risk of serious respiratory depression.DailyMed (U.S. National Library of Medicine)
• Thiazolidinedione antidiabetics (e.g. pioglitazone)Higher frequency of weight gain and peripheral oedema when combined.DailyMed (U.S. National Library of Medicine)
• ACE inhibitorsPossible increased risk of angioedema.DailyMed (U.S. National Library of Medicine)

• Observational data suggest a possible small increase in overall major birth defects without a consistent pattern; a pregnancy exposure registry (NAAED) exists.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Pregabalin passes into human milk; because of tumorigenic potential seen in animals, breastfeeding is not recommended during treatment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha2-delta auxiliary subunit of voltage-gated calcium channels in CNS tissue; does not bind GABA-A, GABA-B or benzodiazepine receptors (US label).