سعر ماتيوجاك 60مجم 3 اقراص 2025

Dapoxetine 60 mg film-coated tablets (3 per pack) by Hochster Pharmaceutical Industries / Novell Pharma, Egypt, used to delay ejaculation in men.

• Treatment of premature ejaculation in adult men aged 18 to 64 years with IELT under 2 minutes, persistent or recurrent ejaculation with minimal stimulation, marked distress, poor control and a 6-month history; on-demand use only; not for men without a diagnosis of premature ejaculation.Population: Adult men 18-64 yearsSwedish Medical Products Agency (Läkemedelsverket)

• Most common and dose related (30 mg / 60 mg): nausea (11.0% / 22.2%), dizziness (5.8% / 10.9%), headache (5.6% / 8.8%), diarrhoea (3.5% / 6.9%), insomnia (2.1% / 3.9%) and fatigue (2.0% / 4.1%); syncope and orthostatic hypotension have been reported.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)

• Hypersensitivity to dapoxetine or any excipient.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)
• Significant cardiac conditions: heart failure (NYHA II-IV), conduction abnormalities (AV block, sick sinus syndrome), significant ischaemic or valvular heart disease, or a history of syncope.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)
• History of mania or severe depression.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)

• Syncope (with bradycardia or sinus arrest) and orthostatic hypotension have occurred, mostly within 3 hours of the first dose; prodromal symptoms include nausea, dizziness, light-headedness and sweating. Patients should lie down or sit with the head low if symptoms occur, stay hydrated and avoid driving or hazardous machinery if affected.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)
• Avoid alcohol: combination with dapoxetine may increase alcohol-related neurocognitive effects and neurocardiogenic events such as syncope.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)
• Should not be used in men with erectile dysfunction who use PDE5 inhibitors (reduced orthostatic tolerance); caution with alpha-blockers.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)

• Moderate CYP3A4 inhibitors (e.g. erythromycin, clarithromycin, fluconazole, amprenavir, fosamprenavir, aprepitant, verapamil, diltiazem)May significantly increase exposure; the maximum dapoxetine dose is 30 mg with these drugs.Swedish Medical Products Agency (Läkemedelsverket)
• Potent CYP2D6 inhibitors (e.g. fluoxetine)Exposure to the active fraction may roughly double; caution if increasing to 60 mg.Swedish Medical Products Agency (Läkemedelsverket)
• PDE5 inhibitors (e.g. sildenafil, tadalafil)Should not be used together because of possible reduced orthostatic tolerance.Swedish Medical Products Agency (Läkemedelsverket)

• Not indicated for use by women; animal studies do not indicate harmful effects on fertility, pregnancy or embryo-fetal development.International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)
• Not known whether dapoxetine or its metabolites are excreted in human milk (product not indicated for women).International label, same formulation · Swedish Medical Products Agency (Läkemedelsverket)

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