سعر ميتفورمين النصر 500مجم 200 قرص 2022

Metformin hydrochloride oral tablets (500 mg per the product name), large pack of 200 tablets (20 strips); Egyptian product by El Nasr Pharmaceutical Chemicals.

• Adjunct to diet and exercise to improve glycaemic control in type 2 diabetes mellitusPopulation: Adults and children 10 years and olderDailyMed (U.S. National Library of Medicine)

• Most common: diarrhoea, nausea/vomiting, flatulence, asthenia, indigestion, abdominal discomfort and headache.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Severe renal impairment (eGFR below 30 mL/min/1.73 m2).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to metformin.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: metformin-associated lactic acidosis; risk factors include renal impairment, age 65 or older, iodinated contrast, surgery, hypoxic states, excessive alcohol and hepatic impairment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Vitamin B12 deficiency may occur; hypoglycaemia risk when combined with insulin or secretagogues.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Iodinated contrast agentsStop metformin at or before the procedure in at-risk patients; restart after 48 hours if renal function is stable.DailyMed (U.S. National Library of Medicine)
• Carbonic anhydrase inhibitors (e.g. topiramate) and drugs reducing metformin clearance (e.g. ranolazine, dolutegravir, cimetidine)May increase metformin exposure or lactic acidosis risk; monitor.DailyMed (U.S. National Library of Medicine)

• Published data have not shown a clear association with major birth defects or miscarriage; poorly controlled diabetes in pregnancy carries maternal and fetal risks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Metformin is present in human milk; no adverse effects reported in breastfed infants in limited data.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Metformin hydrochloride: Decreases hepatic glucose production and intestinal glucose absorption and improves insulin sensitivity (US label).