سعر مترون 0.75% جم جل مهبلي 40 جم 2024

Metronidazole 0.75% vaginal gel (Metron, El Nile); 40 g pack.

• Treatment of bacterial vaginosis.Population: Adult womenDailyMed (U.S. NLM)

• Hypersensitivity to metronidazole, parabens, other formulation ingredients or other nitroimidazole derivatives.International label, same formulation · DailyMed (U.S. NLM)

• Seizures and peripheral neuropathy have been reported with oral/IV metronidazole; discontinue promptly if abnormal neurologic signs appear; caution in CNS disease.International label, same formulation · DailyMed (U.S. NLM)
• Do not give to patients who have taken disulfiram within the last 2 weeks.International label, same formulation · DailyMed (U.S. NLM)
• Severe hepatic disease slows metronidazole metabolism; administer cautiously. Vaginal candidiasis may become more prominent during therapy. Avoid vaginal intercourse during treatment.International label, same formulation · DailyMed (U.S. NLM)

• Warfarin and other coumarin anticoagulantsOral metronidazole potentiates the anticoagulant effect (prolonged prothrombin time); consider with the vaginal gel.DailyMed (U.S. NLM)
• LithiumShort-term oral metronidazole has been associated with raised serum lithium and toxicity in patients on high lithium doses.DailyMed (U.S. NLM)

• Historical Pregnancy Category B: no experience with the vaginal gel in pregnant patients; metronidazole crosses the placenta rapidly; use in pregnancy only if clearly needed.International label, same formulation · DailyMed (U.S. NLM)
• Not studied after vaginal use; oral metronidazole is secreted in milk at plasma-like concentrations; decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. NLM)

• Metronidazole: Reduced inside susceptible anaerobes and protozoa to short-lived reactive intermediates that damage DNA, inhibiting nucleic acid synthesis and causing cell death.