سعر انتوفار 500 مجم 5 بويضات مهبلية 2025

Entophar (metronidazole) 500 mg vaginal ovules, 5 ovules, Pharopharma.

• Reported with metronidazole: headache, dizziness, nausea, abdominal discomfort, metallic taste, vaginal Candida overgrowth (US vaginal gel label, including oral-metronidazole class reactions).General active-ingredient information · DailyMed / FDA

• Prior hypersensitivity to metronidazole, other nitroimidazole derivatives or formulation ingredients (US vaginal gel label).General active-ingredient information · DailyMed / FDA

• Convulsive seizures and peripheral neuropathy have been reported with oral/IV metronidazole; stop if abnormal neurological signs appear and use with caution in CNS disease (US vaginal gel label).General active-ingredient information · DailyMed / FDA
• Vaginal candidiasis may become symptomatic during or after therapy (US vaginal gel label).General active-ingredient information · DailyMed / FDA

• AlcoholDisulfiram-like reaction reported with oral metronidazole; patients should avoid alcohol during treatment (US vaginal gel label).DailyMed / FDA
• DisulfiramPsychotic reactions reported with concurrent disulfiram; do not use in patients who took disulfiram within the last 2 weeks (US vaginal gel label).DailyMed / FDA
• Warfarin and other coumarin anticoagulantsOral metronidazole potentiates the anticoagulant effect (prolonged prothrombin time) (US vaginal gel label).DailyMed / FDA
• LithiumShort-term oral metronidazole has been associated with raised serum lithium and toxicity (US vaginal gel label).DailyMed / FDA

• No experience with the vaginal gel in pregnancy; metronidazole crosses the placenta and enters the fetal circulation rapidly (US vaginal gel label).General active-ingredient information · DailyMed / FDA
• After oral dosing metronidazole is secreted in milk at concentrations similar to plasma; decide whether to discontinue nursing or the drug (US vaginal gel label).General active-ingredient information · DailyMed / FDA

• Metronidazole: After passive diffusion into susceptible anaerobes it is reduced intracellularly (via electron-transport proteins such as ferredoxin) to a short-lived nitroso free radical; the reduced drug and free radicals can interact with DNA, inhibiting DNA synthesis and causing DNA degradation and bacterial death; the precise mechanism is unclear (US label).