سعر امبيكتام 750مجم فيال 2026

Ampicillin + sulbactam 750 mg (total) powder vial for injection (1 vial); penicillin with a beta-lactamase inhibitor.

• Skin and skin-structure infections caused by beta-lactamase-producing strains of S. aureus, E. coli, Klebsiella spp. (including K. pneumoniae), P. mirabilis, B. fragilis, Enterobacter spp. and Acinetobacter calcoaceticusPopulation: Adults and pediatric patients 1 year and olderDailyMed (U.S. National Library of Medicine)
• Intra-abdominal infections caused by beta-lactamase-producing strains of E. coli, Klebsiella spp. (including K. pneumoniae), Bacteroides spp. (including B. fragilis) and Enterobacter spp.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Gynecological infections caused by beta-lactamase-producing strains of E. coli and Bacteroides spp. (including B. fragilis)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Adult clinical trials: pain at the IM injection site (16%), pain at the IV site (3%), thrombophlebitis (3%), phlebitis (1.2%); diarrhea (3%) and rash (<2%) were the most frequent systemic reactions; less than 1% reported itching, nausea, vomiting, candidiasis, fatigue, headache and others.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or other beta-lactams (penicillins, cephalosporins); previous cholestatic jaundice/hepatic dysfunction associated with ampicillin/sulbactam.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have occurred with penicillins, more often in patients with a history of penicillin hypersensitivity or multiple allergies; cross-reactions with cephalosporins are reported. Ask about previous reactions to penicillins, cephalosporins and other allergens before starting; stop the drug if an allergic reaction occurs; serious anaphylaxis requires emergency treatment (epinephrine, oxygen, IV corticosteroids, airway management).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Hepatic dysfunction including hepatitis and cholestatic jaundice has been associated with ampicillin/sulbactam; usually reversible but deaths have been reported; monitor hepatic function regularly in patients with hepatic impairment.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Severe cutaneous adverse reactions (toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS, exfoliative dermatitis, erythema multiforme, AGEP) can occur; monitor patients who develop a rash and stop the drug if lesions progress.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• ProbenecidDecreases renal tubular secretion of ampicillin and sulbactam, resulting in increased and prolonged blood levels.DailyMed (U.S. National Library of Medicine)
• AllopurinolConcurrent use substantially increases the incidence of skin rash compared with ampicillin alone.DailyMed (U.S. National Library of Medicine)
• AminoglycosidesDo not reconstitute together: the ampicillin component inactivates aminoglycosides in vitro.DailyMed (U.S. National Library of Medicine)

• Reproduction studies in mice, rats and rabbits at up to 10 times the human dose showed no impaired fertility or fetal harm; no adequate and well-controlled studies in pregnant women; use in pregnancy only if clearly needed.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Low concentrations of ampicillin and sulbactam are excreted in milk; use with caution in nursing women.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ampicillin: Bactericidal semisynthetic penicillin that acts through inhibition of bacterial cell-wall biosynthesis; active against penicillin-susceptible Gram-positive organisms and many common Gram-negative pathogens; not stable to penicillinases (US ampicillin labels).
• Sulbactam: Irreversibly inhibits a wide range of beta-lactamases; has little useful antibacterial activity alone (except Neisseriaceae) but restores ampicillin activity against beta-lactamase-producing strains (US Unasyn label).