سعر متروفنت استنشاق 25ميكروجرام/جرعة 200 جرعة 2022

• Regular symptomatic add-on treatment of reversible airways obstruction in asthma (including nocturnal asthma) in patients inadequately controlled on inhaled corticosteroids.Population: Adults, adolescents and children aged 4 years and older with asthmaelectronic medicines compendium (eMC)
• Prevention of exercise-induced asthma.Population: Adults, adolescents and children aged 4 years and olderelectronic medicines compendium (eMC)
• Treatment of chronic obstructive pulmonary disease (COPD).Population: Adults aged 18 years and overelectronic medicines compendium (eMC)

• Common: headache, tremor, palpitations and muscle cramps. Uncommon: rash, nervousness, tachycardia. Rare: hypokalaemia, insomnia, dizziness. Very rare: anaphylaxis/angioedema, hyperglycaemia, arrhythmias (including atrial fibrillation), oropharyngeal irritation, paradoxical bronchospasm, nausea, arthralgia, chest pain.International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to salmeterol xinafoate or to any excipient.International label, same formulation · electronic medicines compendium (eMC)

• Not for first-line asthma treatment and not a replacement for inhaled or oral corticosteroids; patients must not stop or reduce steroid therapy without medical advice. Long-acting bronchodilators should not be the only or main maintenance treatment of asthma.International label, same formulation · electronic medicines compendium (eMC)
• Do not start during an acute severe exacerbation or rapidly deteriorating asthma; increasing need for short-acting bronchodilators signals loss of control and needs medical review. Serious asthma-related events can occur during treatment.International label, same formulation · electronic medicines compendium (eMC)
• Paradoxical bronchospasm may occur after dosing: treat immediately with a fast-acting bronchodilator and stop the inhaler.International label, same formulation · electronic medicines compendium (eMC)

• Beta-adrenergic blockersNon-selective and selective beta-blockers may weaken or antagonise salmeterol; avoid unless there are compelling reasons.electronic medicines compendium (eMC)
• Ketoconazole and other potent CYP3A4 inhibitors (e.g. itraconazole, telithromycin, ritonavir)Ketoconazole raised salmeterol AUC about 15-fold; avoid unless benefit outweighs the risk of systemic effects such as QTc prolongation and palpitations.electronic medicines compendium (eMC)
• Xanthine derivatives, corticosteroids and diureticsMay potentiate beta2-agonist hypokalaemia, particularly in acute severe asthma.electronic medicines compendium (eMC)

• Moderate human data (300-1000 pregnancy outcomes) show no malformative or feto/neonatal toxicity; as a precaution it is preferable to avoid use in pregnancy.International label, same formulation · electronic medicines compendium (eMC)
• Salmeterol is excreted in animal milk and a risk to the suckling child cannot be excluded; decide whether to stop breastfeeding or therapy.International label, same formulation · electronic medicines compendium (eMC)

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