سعر موفيجريتال ١٠٠ مجم ٢٠ قرص 100 مجم 2022

Movigretal 100 mg tablets (El Nile / October Pharma): cilostazol for intermittent claudication symptoms.

• Reduction of symptoms of intermittent claudication, as demonstrated by an increased walking distance.DailyMed / FDA

• Most common (≥2% and >placebo at 100 mg BID): headache, diarrhea, abnormal stools, palpitation, dizziness, peripheral edema, others per label.International label, same formulation · DailyMed / FDA

• Heart failure of any severity (boxed warning — PDE3 inhibitors associated with decreased survival in class III–IV HF); hypersensitivity to cilostazol or components.International label, same formulation · DailyMed / FDA

• May cause tachycardia, palpitation, tachyarrhythmia or hypotension; risk of angina/MI exacerbation in ischemic heart disease; LV outflow obstruction reported; monitor CBC for thrombocytopenia/leukopenia; avoid in active bleeding/hemostatic disorders.International label, same formulation · DailyMed / FDA

• Strong/moderate CYP3A4 inhibitors; CYP2C19 inhibitorsMajorIncrease cilostazol exposure; reduce dose to 50 mg twice daily.DailyMed / FDA

• Teratogenic in rats at high multiples of human exposure; no adequate well-controlled studies in pregnant women.International label, same formulation · DailyMed / FDA
• Excreted in rat milk; discontinue nursing or discontinue cilostazol because of potential serious adverse reactions in nursing infants.International label, same formulation · DailyMed / FDA

• Cilostazol: Selective PDE3 inhibitor increasing cAMP; inhibits platelet aggregation and dilates arteries.