سعر كواجيوليس 50مجم 10 اقراص 2022

Coaguless 50 mg 10 scored tabs.: Cilostazol 50 mg (Hikma pharma).

• Reduction of symptoms of intermittent claudication, as indicated by an increased walking distance (US cilostazol labeling). Confirm Egyptian leaflet.Population: AdultsDailyMed (NLM)

• Common: headache, diarrhoea, abnormal stools, infection, rhinitis, pharyngitis, peripheral oedema (US label).International label, same formulation · DailyMed (NLM)

• Congestive heart failure of any severity; hypersensitivity to cilostazol or any component (US label — boxed warning for heart failure).International label, same formulation · DailyMed (NLM)

• Boxed warning: cilostazol is contraindicated in patients with heart failure of any severity; phosphodiesterase III inhibitors have decreased survival in patients with class III–IV CHF (US label).International label, same formulation · DailyMed (NLM)
• May cause tachycardia, palpitation, or hypotension; use caution with other vasodilators or antihypertensives. Bleeding risk may increase with concomitant anticoagulants/antiplatelets.International label, same formulation · DailyMed (NLM)

• CYP3A4 / CYP2C19 inhibitors (e.g. certain azoles, macrolides, omeprazole)MajorMay increase cilostazol exposure; consider dose reduction per US label when strong inhibitors are used.DailyMed (NLM)
• Aspirin / clopidogrel / anticoagulantsModerateAdditive antiplatelet/bleeding effects possible; monitor for bleeding.DailyMed (NLM)

• Cilostazol should be used in pregnancy only if the potential benefit justifies the potential risk; animal studies showed teratogenicity at higher exposures (US label).International label, same formulation · DailyMed (NLM)

• Cilostazol: Selective PDE3 inhibitor increasing cAMP; inhibits platelet aggregation and dilates arteries.