سعر نيفيلوب بلس 5/12.5مجم 20 قرص 2024

Nevilob Plus 5/12.5 mg tablets (Marcyrl): fixed-dose combination of nebivolol hydrochloride 5 mg and hydrochlorothiazide 12.5 mg for hypertension.

• Nebivolol contraindications (UK Nebilet) plus thiazide-related contraindications (anuria, sulphonamide hypersensitivity, severe renal impairment) — confirm on FDC label.General active-ingredient information · MHRA / eMC

• Thiazides may cause electrolyte imbalance, hyperuricaemia, photosensitivity; nebivolol — do not stop abruptly; monitor BP, HR, electrolytes.General active-ingredient information · MHRA / eMC

• Nebivolol: avoid unless clearly necessary. HCTZ crosses the placenta; associated with fetal/neonatal jaundice and thrombocytopenia. FDC generally avoided in pregnancy unless local label states otherwise.General active-ingredient information · MHRA / eMC

• Nebivolol hydrochloride: Beta-adrenergic receptor blocker; antihypertensive mechanism not definitively established (reduced heart rate and contractility, reduced sympathetic outflow, renin suppression, vasodilation) per the US BYSTOLIC label.
• Hydrochlorothiazide: Promotes renal excretion of sodium and chloride, reducing intravascular volume.