سعر اوستيونات بلس 2023

Osteonate Plus (alendronic acid + vitamin D3) tablets by Adwia, Egypt; bisphosphonate for osteoporosis.

• Treatment of osteoporosis in postmenopausal women and treatment to increase bone mass in men with osteoporosis.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (>=3%): abdominal pain, acid regurgitation, constipation, diarrhea, dyspepsia, musculoskeletal pain, nausea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Abnormalities of the esophagus that delay esophageal emptying, such as stricture or achalasia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Inability to stand or sit upright for at least 30 minutes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Hypocalcemia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Upper gastrointestinal adverse reactions (dysphagia, esophagitis, esophageal ulcers) can occur; follow dosing instructions and stop if symptoms develop.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Correct hypocalcemia and other mineral metabolism disturbances before starting; ensure adequate calcium and vitamin D intake.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Severe bone, joint and/or muscle pain may occur.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Calcium supplements, antacids and other multivalent cationsInterfere with alendronate absorption; wait at least 30 minutes after alendronate before taking them.DailyMed (U.S. National Library of Medicine)
• Aspirin / NSAIDsIncreased incidence of upper gastrointestinal adverse events.DailyMed (U.S. National Library of Medicine)

• Available data are insufficient to inform a drug-associated risk; discontinue when pregnancy is recognized.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether alendronate is present in human milk or affects the breastfed infant.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Alendronic acid: Binds bone hydroxyapatite and inhibits osteoclast-mediated bone resorption.
• Cholecalciferol (vitamin D3):