سعر اوكسيبين 5مجم 20 اقراص 2025

Oxybutynin 5 mg tablets (EIPICO, Egypt), antimuscarinic urinary antispasmodic.

• Relief of symptoms of bladder instability (urgency, frequency, leakage, urge incontinence, dysuria) in uninhibited or reflex neurogenic bladderPopulation: Adults and children over 5 yearsDailyMed (US NLM)

• Most common: dry mouth (71%), dizziness, constipation, somnolence, nausea, blurred vision, urinary hesitation/retention, headache.International label, equivalent formulation · DailyMed (US NLM)

• Urinary retention, gastric retention and other severe decreased GI motility conditions, uncontrolled narrow-angle glaucoma, and hypersensitivity to the drug.International label, equivalent formulation · DailyMed (US NLM)

• Angioedema (possibly after the first dose) may be life-threatening; anticholinergic CNS effects (hallucinations, agitation, confusion, somnolence); caution in frail elderly, hepatic/renal impairment, myasthenia gravis, bladder outflow obstruction, GI obstruction, ulcerative colitis, GERD; heat prostration in hot environments.International label, equivalent formulation · DailyMed (US NLM)

• CYP3A4 inhibitors (ketoconazole, itraconazole, erythromycin, clarithromycin)Ketoconazole raised oxybutynin levels 3-4 fold; caution with CYP3A4 inhibitors.DailyMed (US NLM)
• Other anticholinergic drugsAdditive anticholinergic effects (dry mouth, constipation, somnolence).DailyMed (US NLM)

• Safety in pregnancy not established; use only if probable benefit outweighs possible hazards.International label, equivalent formulation · DailyMed (US NLM)
• Unknown whether excreted in human milk; use with caution while nursing.International label, equivalent formulation · DailyMed (US NLM)

• Oxybutynin: Direct antispasmodic effect on smooth muscle and inhibition of the muscarinic action of acetylcholine; increases bladder capacity and reduces uninhibited detrusor contractions.