سعر برانداجليم بلس 25/30مجم 30 قرص 2023

Alogliptin 25 mg / pioglitazone 30 mg film-coated tablets (Prandaglim Plus) by Eva Pharma, Egypt; 30 tablets (3 strips).

• Adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus (not for type 1 diabetes)DailyMed (US NLM)

• Most common (>=4%): nasopharyngitis, back pain, upper respiratory tract infection.International label, same formulation · DailyMed (US NLM)

• Initiation in established NYHA Class III or IV heart failure.International label, same formulation · DailyMed (US NLM)
• History of serious hypersensitivity to alogliptin, pioglitazone or any excipient.International label, same formulation · DailyMed (US NLM)

• Boxed warning: thiazolidinediones cause or exacerbate congestive heart failure; monitor for weight gain, dyspnoea, oedema; not recommended in symptomatic heart failure.International label, same formulation · DailyMed (US NLM)
• Dose-related oedema; increased fracture incidence in women; possible bladder cancer risk (do not use in active bladder cancer); macular oedema reported.International label, same formulation · DailyMed (US NLM)
• Acute pancreatitis has been reported; discontinue promptly if suspected.International label, same formulation · DailyMed (US NLM)

• Limited data with the combination are insufficient to inform drug-associated risk; no adverse developmental effects in animal studies of either component; poorly controlled diabetes carries maternal and fetal risk.International label, same formulation · DailyMed (US NLM)
• No information on pioglitazone or alogliptin in human milk; both are present in rat milk.International label, same formulation · DailyMed (US NLM)