سعر ريسكيور 2مجم 20 قرص 2024

Risperidone 2 mg film-coated tablets, pack of 20, marketed in Egypt by Global Napi Pharmaceuticals.

• Treatment of schizophrenia (adults and adolescents 13-17 years).Population: Adults and adolescentsDailyMed (U.S. National Library of Medicine)
• Acute manic or mixed episodes of Bipolar I disorder, as monotherapy (adults, children 10-17 years) or adjunct to lithium or valproate (adults).Population: Adults and children 10-17 yearsDailyMed (U.S. National Library of Medicine)
• Irritability associated with autistic disorder (children and adolescents 5-17 years).Population: Children and adolescents 5-17 yearsDailyMed (U.S. National Library of Medicine)

• Most common (>5% and twice placebo): parkinsonism, akathisia, dystonia, tremor, sedation, dizziness, anxiety, blurred vision, nausea, vomiting, abdominal pain, dyspepsia, diarrhoea, salivary hypersecretion, constipation, dry mouth, increased appetite and weight, fatigue, rash, nasal congestion, upper respiratory infections.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to risperidone, paliperidone or any excipient (anaphylaxis and angioedema reported).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis; not approved for this use; cerebrovascular events including stroke reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Neuroleptic malignant syndrome and tardive dyskinesia.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Metabolic changes: hyperglycaemia/diabetes, dyslipidaemia and weight gain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Enzyme inducers (carbamazepine, phenytoin, rifampin, phenobarbital)Increase risperidone dose up to double; reduce when the inducer is stopped.DailyMed (U.S. National Library of Medicine)
• Fluoxetine, paroxetine (CYP2D6 inhibitors)Reduce risperidone dose; do not exceed 8 mg/day in adults.DailyMed (U.S. National Library of Medicine)

• Epidemiologic data have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes; a pregnancy exposure registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Risperidone and 9-hydroxyrisperidone are present in milk (relative infant dose 2.3-4.7%); monitor breastfed infants for sedation, failure to thrive, jitteriness and extrapyramidal symptoms.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Risperidone: Mechanism unclear; therapeutic activity may be mediated through combined dopamine D2 and serotonin 5-HT2 receptor antagonism.