سعر ريفوتريل 0.5مجم 50 اقراص 2022
Rivotril 0.5 mgمعلومات الدواء
التفاصيل الكاملةدواعي الاستعمالUses
- Seizure disorders: alone or as adjunctive treatment of Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures; may be useful in absence seizures (petit mal) that have failed to respond to succinimides.DailyMed (U.S. National Library of Medicine)
- Panic disorder, with or without agoraphobia, as defined in DSM-5.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
- Seizure disorders: alone or as adjunctive treatment of Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures; may be useful in absence seizures (petit mal) that have failed to respond to succinimides.DailyMed (U.S. National Library of Medicine)
- Panic disorder, with or without agoraphobia, as defined in DSM-5.Population: AdultsDailyMed (U.S. National Library of Medicine)
الآثار الجانبيةSide effects
- Seizure disorders: most frequent adverse reactions are drowsiness (about 50%), ataxia (about 30%) and behaviour problems (about 25%).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Panic disorder trials: somnolence (37%), depression, coordination abnormal, ataxia, dizziness, fatigue and memory disturbance.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Seizure disorders: most frequent adverse reactions are drowsiness (about 50%), ataxia (about 30%) and behaviour problems (about 25%).International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Panic disorder trials: somnolence (37%), depression, coordination abnormal, ataxia, dizziness, fatigue and memory disturbance.International label, same formulation · DailyMed (U.S. National Library of Medicine)
موانع الاستعمالContraindications
- History of sensitivity to benzodiazepines.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Clinical or biochemical evidence of significant liver disease.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Acute narrow-angle glaucoma (may be used in open-angle glaucoma receiving appropriate therapy).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- History of sensitivity to benzodiazepines.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Clinical or biochemical evidence of significant liver disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Acute narrow-angle glaucoma (may be used in open-angle glaucoma receiving appropriate therapy).International label, same formulation · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطاتWarnings & precautions
- Boxed warning: concomitant use with opioids may result in profound sedation, respiratory depression, coma and death; reserve concomitant prescribing for patients without alternatives and limit dose and duration.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Boxed warning: use exposes users to risks of abuse, misuse and addiction, which can lead to overdose or death; assess each patient's risk before prescribing and throughout treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Boxed warning: continued use may lead to clinically significant physical dependence; abrupt discontinuation or rapid dose reduction may precipitate acute withdrawal reactions, which can be life-threatening; use a gradual taper.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Boxed warning: concomitant use with opioids may result in profound sedation, respiratory depression, coma and death; reserve concomitant prescribing for patients without alternatives and limit dose and duration.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Boxed warning: use exposes users to risks of abuse, misuse and addiction, which can lead to overdose or death; assess each patient's risk before prescribing and throughout treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Boxed warning: continued use may lead to clinically significant physical dependence; abrupt discontinuation or rapid dose reduction may precipitate acute withdrawal reactions, which can be life-threatening; use a gradual taper.International label, same formulation · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائيةDrug interactions
- OpioidsIncreased risk of profound sedation, respiratory depression, coma and death (boxed warning).DailyMed (U.S. National Library of Medicine)
- CNS depressants and alcoholAdditive CNS-depressant effects (other antiepileptics, sedatives, antidepressants, antipsychotics, alcohol).DailyMed (U.S. National Library of Medicine)
- CYP450 inducers (phenytoin, carbamazepine, lamotrigine, phenobarbital)Increase clonazepam clearance, decreasing plasma concentrations by approximately 38% (phenobarbital 19-24%).DailyMed (U.S. National Library of Medicine)
- OpioidsIncreased risk of profound sedation, respiratory depression, coma and death (boxed warning).DailyMed (U.S. National Library of Medicine)
- CNS depressants and alcoholAdditive CNS-depressant effects (other antiepileptics, sedatives, antidepressants, antipsychotics, alcohol).DailyMed (U.S. National Library of Medicine)
- CYP450 inducers (phenytoin, carbamazepine, lamotrigine, phenobarbital)Increase clonazepam clearance, decreasing plasma concentrations by approximately 38% (phenobarbital 19-24%).DailyMed (U.S. National Library of Medicine)
الحمل والرضاعةPregnancy & breastfeeding
- Neonatal sedation and withdrawal syndrome: use late in pregnancy can result in sedation (respiratory depression, lethargy, hypotonia) and/or withdrawal symptoms in the neonate; monitor neonates exposed in utero.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Clonazepam is excreted in human milk; monitor breastfed infants for sedation and poor feeding, and consider the benefits of breastfeeding alongside the mother's clinical need.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Neonatal sedation and withdrawal syndrome: use late in pregnancy can result in sedation (respiratory depression, lethargy, hypotonia) and/or withdrawal symptoms in the neonate; monitor neonates exposed in utero.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Clonazepam is excreted in human milk; monitor breastfed infants for sedation and poor feeding, and consider the benefits of breastfeeding alongside the mother's clinical need.International label, same formulation · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواءHow it works
- Benzodiazepine; precise mechanism not fully understood, believed to be related to enhancement of GABA activity in the CNS (Klonopin USPI section 12.1).
- Clonazepam: Benzodiazepine; precise mechanism not fully understood, believed to be related to enhancement of GABA activity in the CNS (Klonopin USPI section 12.1).
المثائل (3)
كل المثائل والبدائلنفس المادة الفعالة والتركيز. اسأل الصيدلي قبل الاستبدال.
| الدواء | السعر | الفرق عن الأصلي |
|---|---|---|
| روناتريل 0.5مجم 10 اقراصRonatril 0.5 mgHi-Pharm · 0.5 mgالأرخص | السعر1.75ج.م0.18ج.م للوحدة | الفرق عن الأصليأرخص 13.85ج.م (88.8%) |
| سيجوتريل 0.5مجم 10 اقراصSigotryl 0.5 mg 10 tabletsSigma (سيجما) · أقراص · 0.5 mg | السعر1.75ج.م0.18ج.م للوحدة | الفرق عن الأصليأرخص 13.85ج.م (88.8%) |
| كلوزيبام 0.5 مجم 20 قرصKlozepam 0.5 mg tabletsSigma · قرص · 0.5 mg clonazepam per tablet | السعر24ج.م1.2ج.م للوحدة | الفرق عن الأصليأغلى 8.4ج.م (53.8%) |
أدوية ذات صلة
نفس المادة الفعالة بتركيز آخر
منتجات أخرى من F. Hoffmann-La Roche (distributor: Egyptian Pharmaceutical Trading Company)
من فئة مضاد للصرع
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
تعليقات
لا توجد تعليقات بعد. كن أول من يشارك تجربته مع هذا الدواء.
أضف تعليقًا