سعر كلوزيبام 0.5 مجم 20 قرص 2024

Klozepam 0.5 mg tablets (clonazepam), pack of 20, by Sigma (Egypt). Benzodiazepine antiepileptic also used for panic disorder; a controlled medicine with risks of dependence, abuse and withdrawal.

• Seizure disorders: alone or as adjunct in Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures; absence seizures not responding to succinimides.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Panic disorder, with or without agoraphobia.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Seizure disorders: drowsiness (about 50%), ataxia (about 30%) and behaviour problems (about 25%) are the most frequent effects, mostly referable to CNS depression.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of sensitivity to benzodiazepines.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clinical or biochemical evidence of significant liver disease.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Acute narrow-angle glaucoma (may be used in open-angle glaucoma under appropriate therapy).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: concomitant use with opioids may cause profound sedation, respiratory depression, coma and death; reserve for patients without alternatives and limit doses and duration.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: risk of abuse, misuse and addiction, and of physical dependence; abrupt discontinuation or rapid dose reduction can cause life-threatening withdrawal reactions, so taper gradually.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• CNS depression impairs mental alertness: avoid driving or operating machinery, and avoid alcohol and other CNS depressants.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• OpioidsConcomitant use may cause profound sedation, respiratory depression, coma and death.DailyMed (U.S. National Library of Medicine)
• Alcohol and other CNS depressants (barbiturates, hypnotics, antipsychotics, MAO inhibitors, tricyclic antidepressants, other anticonvulsants)CNS-depressant effects may be potentiated.DailyMed (U.S. National Library of Medicine)

• Pregnant patients should inform their prescriber; the US label encourages enrolment in the North American Antiepileptic Drug Pregnancy Registry.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Breastfed infants of treated mothers should be monitored for excessive sedation, poor feeding and poor weight gain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Clonazepam: Benzodiazepine that enhances GABA-mediated inhibition in the CNS (benzodiazepine receptor), producing anticonvulsant, anxiolytic and sedative effects.