سعر سابابريماكس كريم 30 جم 2022

• Topical anaesthesia of normal intact skin for local analgesia, and of genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anaesthesia.Population: Adults and children (per US label)DailyMed (U.S. National Library of Medicine)

• Known sensitivity to amide-type local anaesthetics or to any other component of the product.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Application to larger areas or for longer times than recommended can lead to enough systemic absorption of lidocaine and prilocaine to cause serious adverse effects.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Prilocaine metabolism (ortho-toluidine) can cause methaemoglobinaemia; very young patients, patients with G6PD deficiency and patients taking oxidising drugs (e.g. antimalarials, sulfonamides) are more susceptible.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Not for use where penetration or migration beyond the tympanic membrane into the middle ear is possible (ototoxicity in animal studies).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Class III antiarrhythmics (e.g. amiodarone, sotalol, dofetilide)Cardiac effects may be additive; close surveillance and ECG monitoring should be considered.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies with lidocaine and prilocaine showed no fetal harm, but there are no adequate well-controlled studies in pregnant women; use in pregnancy only if clearly needed.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

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