سعر شيستوسيد 600مجم /5مل معلق 15مل 2022

Schistocide praziquantel 600 mg/5 mL oral suspension, 15 mL bottle, by Delta Pharma (Egypt); an anthelmintic (trematodicide) used against schistosomiasis and liver flukes.

• Schistosomiasis due to all Schistosoma speciesPopulation: Patients aged 1 year and olderDailyMed (U.S. National Library of Medicine)
• Clonorchiasis and opisthorchiasis (liver flukes)Population: Patients aged 1 year and olderDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to praziquantel or excipients.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Ocular cysticercosis (parasite destruction in the eye may cause irreversible lesions).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Concomitant use of strong CYP3A inducers such as rifampin.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Potentially life-threatening clinical deterioration when treated during the acute phase of schistosomiasis; possible lack of efficacy in acute schistosomiasis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• May exacerbate CNS pathology (e.g. epilepsy, possible cysticercosis); cardiac arrhythmias have been reported; caution in hepatosplenic schistosomiasis with hepatic impairment.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A inducers (e.g. rifampin)Concomitant use is contraindicated because it may markedly reduce praziquantel exposure.DailyMed (U.S. National Library of Medicine)

• Published studies have not identified an association with use in pregnancy and major birth defects, miscarriage or adverse maternal/fetal outcomes; no adverse developmental outcomes in rat and rabbit studies.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Praziquantel is present in human milk at low concentrations; no information on effects in the breastfed infant; weigh benefits of breastfeeding against maternal need.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Praziquantel: Induces rapid contraction of schistosomes via cell-membrane permeability effects; tegument vacuolization/disintegration.