سعر ساينسستات 40مجم 7 كبسولات 2022

Sciencestat (Delta Pharma / Science Pharma, Egypt): fluvastatin 40 mg capsules, pack of 7; an HMG-CoA reductase inhibitor (statin) used to lower blood cholesterol.

• Adjunct to diet to reduce elevated total cholesterol, LDL-C, Apo B and triglycerides and increase HDL-C in primary hypercholesterolaemia and mixed dyslipidaemiaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunct to diet to reduce total cholesterol, LDL-C and Apo B in heterozygous familial hypercholesterolaemia after an adequate trial of dietPopulation: Boys and post-menarchal girls 10-16 yearsDailyMed (U.S. National Library of Medicine)
• Reduce the risk of coronary revascularisation procedures and slow the progression of coronary atherosclerosis in patients with clinically evident coronary heart diseasePopulation: Adults with coronary heart diseaseDailyMed (U.S. National Library of Medicine)

• Most frequent adverse reactions (2% or more and more than placebo): headache, dyspepsia, myalgia, abdominal pain and nausea; also reported diarrhoea, insomnia, fatigue and flatulence.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Active liver disease or unexplained persistent elevations of serum transaminases.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Pregnancy or women who may become pregnant.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Myopathy and rhabdomyolysis: risk increases with age 65 or older, uncontrolled hypothyroidism, renal impairment, and with cyclosporine, gemfibrozil/fibrates, niacin or erythromycin; report unexplained muscle pain, tenderness or weakness and stop if myopathy is suspected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Rare immune-mediated necrotising myopathy (IMNM) has been reported with statins.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Liver enzyme abnormalities: check liver enzymes before starting and as clinically indicated; interrupt therapy if serious liver injury with symptoms, hyperbilirubinaemia or jaundice occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• CyclosporineIncreases fluvastatin exposure; limit fluvastatin to 20 mg twice daily.DailyMed (U.S. National Library of Medicine)
• FluconazoleIncreases fluvastatin exposure; limit fluvastatin to 20 mg twice daily.DailyMed (U.S. National Library of Medicine)
• Fibrates (e.g. gemfibrozil) and lipid-modifying doses of niacin (1 g/day or more)Increased risk of skeletal muscle effects; use with caution.DailyMed (U.S. National Library of Medicine)

• Contraindicated in women who are pregnant or may become pregnant; may cause fetal harm. If pregnancy occurs, stop treatment and inform the patient of the potential hazard. Use in women of childbearing age only when conception is highly unlikely.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Contraindicated in nursing mothers: fluvastatin passes into animal milk (about 2:1 milk:plasma) and statins may cause serious adverse reactions in nursing infants.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Fluvastatin: Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme converting HMG-CoA to mevalonate; reduced hepatic cholesterol up-regulates LDL receptors and lowers plasma cholesterol (US fluvastatin capsules label).