سعر شامسوموكس 400مجم 10 اقراص 2025

Shamsomox 400 mg 10 film-coated tablets: moxifloxacin 400 mg film-coated tablets, pack of 10, listed in Egypt under El Shams Trading; a fluoroquinolone antibacterial.

• Community-acquired pneumonia caused by susceptible bacteriaPopulation: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Uncomplicated skin and skin-structure infectionsPopulation: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Complicated skin and skin-structure infectionsPopulation: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)

• Common adverse reactions include nausea, diarrhoea, headache and dizziness; nausea, diarrhoea, dizziness and vomiting were the most common reasons for stopping oral 400 mg.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to moxifloxacin or any other quinolone antibacterial.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: disabling and potentially irreversible serious reactions including tendinitis and tendon rupture, peripheral neuropathy and CNS effects; may exacerbate myasthenia gravis (avoid in known myasthenia gravis). Discontinue at first signs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Prolongs the QT interval: avoid in known QT prolongation, uncorrected hypokalaemia/hypomagnesaemia and with class IA/III antiarrhythmics.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serious hypersensitivity/anaphylaxis and other serious reactions (severe skin reactions, hepatitis, haematological effects) can occur; stop at first rash.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids, sucralfate, iron, zinc, multivitamins (multivalent cations)Chelation markedly reduces moxifloxacin absorption; separate doses (4 h before / 8 h after).DailyMed (U.S. National Library of Medicine)
• WarfarinMay enhance anticoagulant effect; monitor PT/INR.DailyMed (U.S. National Library of Medicine)
• Antidiabetic agentsHypo- or hyperglycaemia; monitor blood glucose.DailyMed (U.S. National Library of Medicine)

• No human data establishing a drug-associated risk; based on animal studies (fetal loss, reduced neonatal weight, skeletal variations at maternally toxic doses) moxifloxacin may cause fetal harm.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether present in human milk; very low excretion in rat milk; weigh benefits of breastfeeding against maternal need and possible infant effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Moxifloxacin: Bactericidal; inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes needed for DNA replication, transcription, repair and recombination.