سعر سيلدين 50مجم 4 اقراص ذائبة فموية 2022

Silden 50 mg orodispersible tablets (sildenafil), pack of 4, by EIPICO (Egypt); a phosphodiesterase type 5 inhibitor that disintegrates in the mouth.

• Treatment of erectile dysfunction in adult men (sexual stimulation is required for efficacy).Population: Adult menEuropean Medicines Agency (EMA)

• Most commonly reported in clinical studies: headache, flushing, dyspepsia, nasal congestion, dizziness, nausea, hot flush, visual disturbance, cyanopsia and blurred vision.International label, same formulation · European Medicines Agency (EMA)

• Hypersensitivity to sildenafil or to any of the excipients.International label, same formulation · European Medicines Agency (EMA)
• Co-administration with nitric oxide donors (such as amyl nitrite) or nitrates in any form.International label, same formulation · European Medicines Agency (EMA)
• Co-administration with guanylate cyclase stimulators such as riociguat.International label, same formulation · European Medicines Agency (EMA)

• Consider cardiovascular status before treatment, since sexual activity carries a degree of cardiac risk; sildenafil causes mild, transient decreases in blood pressure.International label, same formulation · European Medicines Agency (EMA)
• Use with caution in anatomical deformation of the penis or conditions predisposing to priapism; an erection persisting longer than 4 hours needs immediate medical help.International label, same formulation · European Medicines Agency (EMA)
• Co-administration with ritonavir is not advised; consider a 25 mg starting dose with other CYP3A4 inhibitors, and stabilise patients on alpha-blockers before starting sildenafil (consider 25 mg).International label, same formulation · European Medicines Agency (EMA)

• Nitrates or nitric oxide donors (e.g. amyl nitrite)Sildenafil potentiates their hypotensive effects; co-administration is contraindicated.European Medicines Agency (EMA)
• RitonavirCo-administration with sildenafil is not advised.European Medicines Agency (EMA)
• CYP3A4 inhibitorsA starting dose of 25 mg should be considered.European Medicines Agency (EMA)

• Not indicated for use by women; there are no adequate and well-controlled studies in pregnant or breast-feeding women, and no relevant adverse effects were found in rat and rabbit reproduction studies.International label, same formulation · European Medicines Agency (EMA)
• Not indicated for use in females; limited data indicate sildenafil and its active metabolite are present in human milk, with no information on effects on the breastfed child.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Sildenafil: Inhibits PDE5, the enzyme that degrades cGMP in the corpus cavernosum, enhancing the nitric oxide effect during sexual stimulation (smooth-muscle relaxation and inflow of blood).