سعر سنافي 20 مجم 2 قرص 2025

Snafi 20 mg film-coated tablets, pack of 2 (tadalafil), SPIMACO product listed with EIMC in Egypt; a PDE5 inhibitor used for erectile dysfunction.

• Erectile dysfunctionPopulation: Adult menDailyMed (U.S. National Library of Medicine)

• As-needed ED trials, 20 mg: headache 15%, dyspepsia 10%, back pain 6%, myalgia 3%, nasal congestion 3%, flushing 3%, pain in limb 3%.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Any form of organic nitrate, regularly or intermittently.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Known serious hypersensitivity to tadalafil (Stevens-Johnson syndrome and exfoliative dermatitis reported).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant guanylate cyclase stimulators such as riociguat.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Consider cardiovascular status; not for men in whom sexual activity is inadvisable; if nitrates are needed for a life-threatening situation, at least 48 hours should have elapsed after the last dose.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Erection >4 hours or priapism requires emergency care; caution in conditions predisposing to priapism or with penile deformation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Stop and seek medical attention for sudden vision loss (possible NAION) or sudden decrease/loss of hearing.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Organic nitratesContraindicated: potentiates the hypotensive effect of nitrates.DailyMed (U.S. National Library of Medicine)
• Alpha-blockersFor ED, patients should be stable on alpha-blocker therapy and tadalafil started at the lowest dose.DailyMed (U.S. National Library of Medicine)
• Potent CYP3A4 inhibitors (ketoconazole, ritonavir, itraconazole)Increase exposure; as-needed maximum 10 mg once every 72 hours.DailyMed (U.S. National Library of Medicine)

• Not indicated for use in females; no data in pregnant women; no adverse developmental effects in rats or mice at up to 11 times the maximum recommended human dose.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Not indicated for use in females; no information on presence in human milk; present in rat milk at about 2.4-fold plasma levels.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Tadalafil: Inhibits PDE5, increasing cGMP in corpus cavernosum and prostate/bladder smooth muscle (US CIALIS).