سعر سورديفان 320مجم 7 اقراص 2022

Valsartan 320 mg film-coated tablets, pack of 7; Hikma Pharma / Atos Pharma, Egypt.

• Hypertension, to lower blood pressure (reducing the risk of fatal and nonfatal cardiovascular events, mainly strokes and myocardial infarctions).Population: Adults and children 1 year and olderDailyMed (U.S. National Library of Medicine)
• Heart failure (NYHA class II-IV), to reduce hospitalisation for heart failure.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Post-myocardial infarction: reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or dysfunction.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypertension: most common headache, dizziness, viral infection, fatigue and abdominal pain. Heart failure: dizziness, hypotension, diarrhoea, arthralgia, back pain, fatigue and hyperkalaemia. Post-MI: hypotension, cough and increased blood creatinine were the commonest reasons for discontinuation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not coadminister aliskiren with valsartan in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Fetal toxicity: drugs acting on the renin-angiotensin system in the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypotension may occur in volume- or salt-depleted patients (e.g. high-dose diuretics); correct depletion first or start under close supervision.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Changes in renal function including acute renal failure, particularly with renal artery stenosis, chronic kidney disease, severe heart failure or volume depletion.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• NSAIDs including COX-2 inhibitorsIn elderly, volume-depleted or renally impaired patients may worsen renal function (possible acute renal failure) and may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)
• Dual RAS blockade (ACE inhibitors, other ARBs, aliskiren)Increased risk of hypotension, hyperkalaemia and renal function changes; generally avoid; aliskiren is contraindicated in diabetes and should be avoided with GFR below 60 mL/min.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; RAS-acting drugs in the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; cases of oligohydramnios/anhydramnios reported with valsartan. Consider alternative treatment and discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human data; valsartan is present in rat milk. Breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Valsartan: Blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking its binding to the AT1 receptor.