سعر لازاروميب 160 مجم 14 قرص 2022

Valsartan 160 mg film-coated tablets, pack of 14, by Mepaco (Egypt); angiotensin II receptor blocker.

• Hypertension in adults and paediatric patients 1 year of age and older, to lower blood pressure.Population: Adults and children >=1 yearDailyMed (U.S. National Library of Medicine)
• Heart failure (NYHA class II-IV), to reduce hospitalisation for heart failure.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Clinically stable patients with left ventricular failure or dysfunction following myocardial infarction, to reduce cardiovascular mortality.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypertension trials: viral infection (3%), fatigue (2%) and abdominal pain (2%) occurred more often than placebo; headache and dizziness were the most common reasons for discontinuation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not co-administer aliskiren with valsartan in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• BOXED WARNING - fetal toxicity: drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus; discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur in volume- or salt-depleted patients (e.g. on high-dose diuretics) and in heart failure or post-MI patients; correct depletion before starting.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Changes in renal function including acute renal failure can occur, particularly in patients whose renal function depends on RAS activity (e.g. renal artery stenosis, severe heart failure); monitor renal function.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potassium-sparing diuretics, potassium supplements, salt substitutes and other potassium-raising drugsMay increase serum potassium; monitor potassium.DailyMed (U.S. National Library of Medicine)
• NSAIDs including selective COX-2 inhibitorsMay worsen renal function (including acute renal failure) in elderly, volume-depleted or renally impaired patients and may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)
• Dual RAS blockade (ACE inhibitors, other ARBs, aliskiren)Increased risk of hypotension, hyperkalaemia and renal function changes; avoid combined use in most patients.DailyMed (U.S. National Library of Medicine)

• Use of RAS-acting drugs in the second and third trimesters reduces fetal renal function and increases fetal and neonatal morbidity and death; discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk; present in rat milk. Breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Valsartan: Angiotensin II receptor blocker: selectively blocks binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects.