سعر سبيريفا 18مكجم 30 كبسولة + جهاز 2026

Spiriva 18 mcg inhalation capsules (Boehringer Ingelheim), 30 capsules with HandiHaler inhaler device: tiotropium, a long-acting inhaled anticholinergic bronchodilator for COPD maintenance.

• Long-term, once-daily maintenance treatment of bronchospasm associated with COPD (including chronic bronchitis and emphysema) and reduction of COPD exacerbations.Population: Adults with COPDDailyMed (U.S. National Library of Medicine)

• Most common (>5% in 1-year placebo-controlled trials): upper respiratory tract infection, dry mouth, sinusitis, pharyngitis, non-specific chest pain, urinary tract infection, dyspepsia, rhinitis. Post-marketing: glossitis, mouth ulceration, pharyngolaryngeal pain, dizziness, dysphagia, hoarseness, intestinal obstruction including paralytic ileus, increased intraocular pressure, oral candidiasis, palpitations, pruritus, tachycardia, throat irritation, urticaria.International label, same product · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to tiotropium, ipratropium or any component of the product.International label, same product · DailyMed (U.S. National Library of Medicine)

• Not for acute use: once-daily maintenance treatment, not rescue therapy for acute bronchospasm.International label, same product · DailyMed (U.S. National Library of Medicine)
• Immediate hypersensitivity reactions (urticaria, angioedema, rash, bronchospasm, anaphylaxis, itching) may occur; stop at once. Monitor patients with hypersensitivity to atropine or its derivatives.International label, same product · DailyMed (U.S. National Library of Medicine)
• Paradoxical bronchospasm may occur; treat immediately with an inhaled short-acting beta2-agonist and stop the drug.International label, same product · DailyMed (U.S. National Library of Medicine)

• Other anticholinergic-containing drugsPotential additive anticholinergic effects; avoid co-administration.DailyMed (U.S. National Library of Medicine)
• Sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroidsUsed concomitantly in trials without increases in adverse reactions.DailyMed (U.S. National Library of Medicine)

• Limited human data are insufficient to inform a drug-associated risk; no structural abnormalities in rats and rabbits at inhaled doses about 790 and 8 times the maximum recommended human daily inhalation dose; post-implantation loss at maternally toxic doses.International label, same product · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant; tiotropium is present in rat milk. Weigh benefits of breastfeeding against the mother's need and potential infant effects.International label, same product · DailyMed (U.S. National Library of Medicine)

• Tiotropium bromide: Long-acting muscarinic antagonist: inhibits M3 receptors at bronchial smooth muscle, producing bronchodilation (US label pharmacology class: anticholinergic).