سعر ستربتومايسين مصر 1جم فيال 2023

Streptomycin-misr 1gm vial usp 24: streptomycin 1 g vial (Misr, Egypt), an aminoglycoside antibiotic powder for intramuscular injection, used mainly as part of combination regimens for tuberculosis and for certain serious infections such as plague, tularaemia and brucellosis.

• Tuberculosis (Mycobacterium tuberculosis), as part of a combination regimenDailyMed (US National Library of Medicine)
• Plague (Yersinia pestis) and tularaemia (Francisella tularensis)DailyMed (US National Library of Medicine)
• Brucellosis, donovanosis and chancroidDailyMed (US National Library of Medicine)

• Common: vestibular ototoxicity (nausea, vomiting, vertigo), facial paraesthesia, rash, fever, urticaria, angioedema, eosinophilia. Less frequent: deafness, exfoliative dermatitis, anaphylaxis, azotaemia, blood dyscrasias, muscular weakness, amblyopia.International label, same formulation · DailyMed (US National Library of Medicine)

• Clinically significant hypersensitivity to streptomycin; hypersensitivity to other aminoglycosides may also contraindicate use (cross-sensitivity).International label, same formulation · DailyMed (US National Library of Medicine)

• Boxed warning: severe neurotoxic reactions (vestibular and cochlear damage, optic nerve dysfunction, peripheral neuritis, encephalopathy) and neuromuscular blockade with respiratory paralysis can occur, especially in renal impairment.International label, same formulation · DailyMed (US National Library of Medicine)
• Ototoxicity is dose- and duration-related and is potentiated by ethacrynic acid, furosemide, mannitol and possibly other diuretics; patients with mitochondrial MT-RNR1 variants (e.g. m.1555A>G) are at higher risk.International label, same formulation · DailyMed (US National Library of Medicine)
• Clostridioides difficile-associated diarrhoea has been reported and may occur up to two months after treatment.International label, same formulation · DailyMed (US National Library of Medicine)

• Other neurotoxic/nephrotoxic drugs (neomycin, kanamycin, gentamicin, tobramycin, polymyxin B, colistin, cyclosporine, etc.)Concurrent or sequential use should be avoided (additive neuro- and nephrotoxicity).DailyMed (US National Library of Medicine)
• Ethacrynic acid, furosemide, mannitol and other diureticsPotentiate aminoglycoside ototoxicity.DailyMed (US National Library of Medicine)

• Streptomycin can cause fetal harm: it crosses the placenta and may cause fetal ototoxicity; patients must be told of the hazard if used in pregnancy.International label, same formulation · DailyMed (US National Library of Medicine)
• Because of potential serious adverse reactions in nursing infants, decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (US National Library of Medicine)

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