سعر ستربتومايسين سلفات سيد 1جم فيال 2022

Streptomycin sulphate 1 g powder in a vial for intramuscular injection (CID, Egypt); aminoglycoside antibiotic used mainly for tuberculosis and certain serious bacterial infections.

• Mycobacterium tuberculosis infection, as part of a multidrug regimen (e.g. added as a fourth drug when resistance is suspected).Population: Adults and childrenDailyMed (US National Library of Medicine)
• Moderate to severe non-tuberculous infections from susceptible organisms, including plague, tularaemia, brucellosis, granuloma inguinale, chancroid, and (with other agents) certain urinary, respiratory and endocardial infections.Population: Adults and childrenDailyMed (US National Library of Medicine)

• Common: vestibular ototoxicity (nausea, vomiting, vertigo), facial paraesthesia, rash, fever, urticaria, angioedema, eosinophilia. Less frequent: deafness, exfoliative dermatitis, anaphylaxis, azotaemia, blood dyscrasias, muscle weakness, amblyopia.International label, same formulation · DailyMed (US National Library of Medicine)

• History of clinically significant hypersensitivity to streptomycin; hypersensitivity to other aminoglycosides may contraindicate use (cross-sensitivity).International label, same formulation · DailyMed (US National Library of Medicine)

• Boxed warning: risk of severe neurotoxicity (vestibular and cochlear damage, optic nerve dysfunction, peripheral neuritis, encephalopathy) is sharply increased in renal impairment; irreversible vestibular damage is particularly frequent. Neuromuscular blockade can cause respiratory paralysis.International label, same formulation · DailyMed (US National Library of Medicine)
• Avoid concurrent or sequential use of other neurotoxic/nephrotoxic drugs (e.g. neomycin, kanamycin, gentamicin, tobramycin, polymyxin B, colistin, cyclosporine); ototoxicity is potentiated by ethacrynic acid, furosemide, mannitol and possibly other diuretics.International label, same formulation · DailyMed (US National Library of Medicine)
• Clostridioides difficile-associated diarrhoea has been reported.International label, same formulation · DailyMed (US National Library of Medicine)

• Loop/osmotic diuretics (ethacrynic acid, furosemide, mannitol)Potentiate the ototoxicity of streptomycin.DailyMed (US National Library of Medicine)

• Streptomycin can cause fetal harm; it crosses the placenta and can cause fetal ototoxicity. Patients should be told of the potential hazard if used in pregnancy.International label, same formulation · DailyMed (US National Library of Medicine)
• Because of potential serious adverse reactions in nursing infants, decide whether to stop nursing or the drug.International label, same formulation · DailyMed (US National Library of Medicine)

• Streptomycin (as sulphate): Bactericidal; inhibits bacterial protein synthesis.