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معلومات الدواء

الآثار الجانبيةSide effects
  • Post-marketing reactions include nausea, vomiting, abdominal pain, gastro-oesophageal reflux, headache, insomnia, tremor, dizziness, tachycardia, palpitations, arrhythmias, seizures, hypokalaemia, hyperuricaemia, rash and diuresis.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Post-marketing reactions include nausea, vomiting, abdominal pain, gastro-oesophageal reflux, headache, insomnia, tremor, dizziness, tachycardia, palpitations, arrhythmias, seizures, hypokalaemia, hyperuricaemia, rash and diuresis.General active-ingredient information · electronic Medicines Compendium (eMC)
موانع الاستعمالContraindications
  • Hypersensitivity to theophylline, other xanthines or excipients; porphyria; concomitant ephedrine in children under 6 years; children under 6 months.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Hypersensitivity to theophylline, other xanthines or excipients; porphyria; concomitant ephedrine in children under 6 years; children under 6 months.General active-ingredient information · electronic Medicines Compendium (eMC)
تحذيرات واحتياطاتWarnings & precautions
  • Dose reduction and level monitoring may be needed in the elderly and in cardiac disease, hepatic disease, hypothyroidism, fever, viral infection or hypokalaemia risk; dose increase may be needed in hyperthyroidism, cystic fibrosis and smokers.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Caution in peptic ulcer, arrhythmias, epilepsy, severe hypertension, chronic alcoholism and elderly men with prostatic enlargement (urinary retention).معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Dose reduction and level monitoring may be needed in the elderly and in cardiac disease, hepatic disease, hypothyroidism, fever, viral infection or hypokalaemia risk; dose increase may be needed in hyperthyroidism, cystic fibrosis and smokers.General active-ingredient information · electronic Medicines Compendium (eMC)
  • Caution in peptic ulcer, arrhythmias, epilepsy, severe hypertension, chronic alcoholism and elderly men with prostatic enlargement (urinary retention).General active-ingredient information · electronic Medicines Compendium (eMC)
التداخلات الدوائيةDrug interactions
  • Cimetidine, ciprofloxacin/enoxacin, erythromycin/clarithromycin, fluvoxamine, allopurinol, diltiazem, verapamil, oral contraceptives and other clearance inhibitorsRaise theophylline levels; dose reduction and monitoring may be needed; avoid fluvoxamine where possible.electronic Medicines Compendium (eMC)
  • Carbamazepine, phenytoin, rifampicin, ritonavir, barbiturates, St John's wort, smoking, alcoholIncrease theophylline clearance; higher doses may be needed.electronic Medicines Compendium (eMC)
  • Beta-2 agonists, corticosteroids, diureticsHypokalaemia may be potentiated by xanthines.electronic Medicines Compendium (eMC)
  • Cimetidine, ciprofloxacin/enoxacin, erythromycin/clarithromycin, fluvoxamine, allopurinol, diltiazem, verapamil, oral contraceptives and other clearance inhibitorsRaise theophylline levels; dose reduction and monitoring may be needed; avoid fluvoxamine where possible.electronic Medicines Compendium (eMC)
  • Carbamazepine, phenytoin, rifampicin, ritonavir, barbiturates, St John's wort, smoking, alcoholIncrease theophylline clearance; higher doses may be needed.electronic Medicines Compendium (eMC)
  • Beta-2 agonists, corticosteroids, diureticsHypokalaemia may be potentiated by xanthines.electronic Medicines Compendium (eMC)
الحمل والرضاعةPregnancy & breastfeeding
  • No adequate data in pregnant women; teratogenic in animals; do not use in pregnancy unless clearly necessary; neonatal irritability and apnoea reported.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Secreted in breast milk and may cause infant irritability; use only if benefit outweighs risk.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • No adequate data in pregnant women; teratogenic in animals; do not use in pregnancy unless clearly necessary; neonatal irritability and apnoea reported.General active-ingredient information · electronic Medicines Compendium (eMC)
  • Secreted in breast milk and may cause infant irritability; use only if benefit outweighs risk.General active-ingredient information · electronic Medicines Compendium (eMC)
المتابعة أثناء العلاجMonitoring
  • Target plasma theophylline 10-20 micrograms/ml (5-15 may be effective); monitor levels at higher doses, impaired clearance or with interacting drugs; monitor potassium in severe asthma.معلومة عامة عن المادة الفعالة · electronic Medicines Compendium (eMC)
  • Target plasma theophylline 10-20 micrograms/ml (5-15 may be effective); monitor levels at higher doses, impaired clearance or with interacting drugs; monitor potassium in severe asthma.General active-ingredient information · electronic Medicines Compendium (eMC)

تابع أسعار الأدوية أول بأول

بننشر كل يوم أسعار أدوية اتغيرت والبدائل الأرخص

نفس المادة الفعالة والتركيز. اسأل الصيدلي قبل الاستبدال.

مثائل Xanthium SR 400 mg 10 caps بنفس المادة الفعالة والتركيز، مرتبة من الأرخص
يونيفيللين 400مجم 20 قرصUniphyllin continus 400mg 20 contr. rel. tabsmundipharma · أقراص ممتدة المفعول · 400 mgالأرخصشكل مختلفالسعر15ج.م0.75ج.م للوحدةالفرق عن الأصليأغلى 12ج.م (400%)

المصادر

تعليقات

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أضف تعليقًا

0/60

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0/1000

من 20 إلى 1000 حرف. بدون روابط.

التعليقات للمعلومات العامة ولا تُعد نصيحة طبية. لا تذكر بيانات شخصية.