سعر يونيفيللين Uniphyllin continus‏ 400مجم 20 قرص 2026

Theophylline 400 mg prolonged-release tablets (El Nile / Mundipharma).

• Post-marketing reactions include nausea, vomiting, abdominal pain, gastro-oesophageal reflux, headache, insomnia, tremor, dizziness, tachycardia, palpitations, arrhythmias, seizures, hypokalaemia, hyperuricaemia, rash and diuresis.International label, same formulation · electronic Medicines Compendium (eMC)

• Hypersensitivity to theophylline, other xanthines or excipients; porphyria; concomitant ephedrine in children under 6 years; children under 6 months.International label, same formulation · electronic Medicines Compendium (eMC)

• Dose reduction and level monitoring may be needed in the elderly and in cardiac disease, hepatic disease, hypothyroidism, fever, viral infection or hypokalaemia risk; dose increase may be needed in hyperthyroidism, cystic fibrosis and smokers.International label, same formulation · electronic Medicines Compendium (eMC)
• Caution in peptic ulcer, arrhythmias, epilepsy, severe hypertension, chronic alcoholism and elderly men with prostatic enlargement (urinary retention).International label, same formulation · electronic Medicines Compendium (eMC)

• Cimetidine, ciprofloxacin/enoxacin, erythromycin/clarithromycin, fluvoxamine, allopurinol, diltiazem, verapamil, oral contraceptives and other clearance inhibitorsRaise theophylline levels; dose reduction and monitoring may be needed; avoid fluvoxamine where possible.electronic Medicines Compendium (eMC)
• Carbamazepine, phenytoin, rifampicin, ritonavir, barbiturates, St John's wort, smoking, alcoholIncrease theophylline clearance; higher doses may be needed.electronic Medicines Compendium (eMC)
• Beta-2 agonists, corticosteroids, diureticsHypokalaemia may be potentiated by xanthines.electronic Medicines Compendium (eMC)

• No adequate data in pregnant women; teratogenic in animals; do not use in pregnancy unless clearly necessary; neonatal irritability and apnoea reported.International label, same formulation · electronic Medicines Compendium (eMC)
• Secreted in breast milk and may cause infant irritability; use only if benefit outweighs risk.International label, same formulation · electronic Medicines Compendium (eMC)