سعر ALDOSPIRA 50 MG 20 TABS. 2026

Aldospira 50 mg, 20 tablets of eplerenone (Saja Pharmaceuticals); selective aldosterone receptor antagonist.

• HFrEF post-MI: hyperkalaemia and increased creatinine most common; adverse reactions uncommon in hypertension studies.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• All patients: serum potassium >5.5 mEq/L at initiation, creatinine clearance <=30 mL/min, strong CYP3A inhibitors. Hypertension: type 2 diabetes with microalbuminuria, raised serum creatinine, CrCl <50 mL/min, potassium supplements or potassium-sparing diuretics.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hyperkalaemia: higher risk with renal impairment, proteinuria, diabetes, ACE inhibitors, ARBs, NSAIDs and moderate CYP3A inhibitors; monitor potassium and adjust dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Moderate CYP3A inhibitors (verapamil, erythromycin, fluconazole, saquinavir)Post-MI HFrEF: do not exceed 25 mg once daily; hypertension: start 25 mg once daily, max 25 mg twice daily.DailyMed (U.S. National Library of Medicine)
• Strong CYP3A inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir, nelfinavir)Contraindicated.DailyMed (U.S. National Library of Medicine)

• No human data on presence in milk; eplerenone is present in rat milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Eplerenone: Binds the mineralocorticoid receptor and blocks aldosterone binding (US Inspra label).