سعر فاركودارون 200 مجم 30 قرص 2022

Amiodarone 200 mg tablets (class III antiarrhythmic), pack of 30.

• Life-threatening recurrent ventricular fibrillation and recurrent haemodynamically unstable ventricular tachycardia in adults refractory to or intolerant of other antiarrhythmics.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Serious adverse reactions include pulmonary toxicity, hepatic injury, worsened arrhythmia, visual impairment/loss of vision, thyroid abnormalities, bradycardia, peripheral neuropathy, photosensitivity and skin discoloration.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cardiogenic shock; sick sinus syndrome, second- or third-degree AV block, or bradycardia leading to syncope without a functioning pacemaker; known hypersensitivity to the drug or any component, including iodine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: for use only in the indicated life-threatening arrhythmias because of substantial toxicity. Pulmonary toxicity (hypersensitivity or interstitial/alveolar pneumonitis) may be fatal; hepatotoxicity may be fatal; amiodarone can exacerbate arrhythmias and should be initiated in a clinical setting with continuous ECG monitoring.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• WarfarinAmiodarone increases warfarin exposure; monitor prothrombin time/INR and reduce warfarin dose as needed (ingredient-level interaction listed in the shared cache from US labels).DailyMed (U.S. National Library of Medicine)
• DigoxinAmiodarone can increase digoxin concentrations; monitor and reduce digoxin dose as needed.DailyMed (U.S. National Library of Medicine)
• Sofosbuvir-containing regimensSerious symptomatic bradycardia has been reported when amiodarone is co-administered with sofosbuvir-containing regimens.DailyMed (U.S. National Library of Medicine)

• Use in pregnancy may increase the risk of fetal adverse effects including neonatal hypo- and hyperthyroidism, neonatal bradycardia, neurodevelopmental abnormalities, preterm birth and fetal growth restriction; amiodarone and desethylamiodarone cross the placenta.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Amiodarone and desethylamiodarone are present in breast milk at 3.5-45% of the maternal weight-adjusted dose; hypothyroidism and bradycardia have been reported in breastfed infants. Breastfeeding is not recommended.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amiodarone (as hydrochloride): Prolongs the cardiac action potential and refractoriness (class III effect) by blocking myocardial potassium channels; also blocks sodium channels at rapid rates, has non-competitive antisympathetic action and slows nodal conduction (class I, II and IV-like effects).