سعر انتودين antodine‏ 40مجم/5مل بودرة لعمل معلق 60 مل للحموضة والتهاب المعدة 2026

peptic ulcer.anti-histamine.h2 antagonist

• Most common adverse reactions: headache, dizziness, constipation and diarrhoea.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g. anaphylaxis) to famotidine or other H2-receptor antagonists.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Central nervous system adverse reactions (confusion, delirium, hallucinations, disorientation, agitation, seizures, lethargy) reported in elderly patients and patients with moderate-severe renal impairment; reduce dosage.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic response to famotidine does not preclude gastric malignancy; consider evaluation before starting therapy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tizanidine (CYP1A2 substrate)Famotidine is a weak CYP1A2 inhibitor; avoid concomitant use with tizanidine (risk of hypotension, bradycardia, excessive drowsiness) unless clinically necessary.DailyMed (U.S. National Library of Medicine)
• Drugs with pH-dependent absorption (e.g. dasatinib, delavirdine, cefditoren, fosamprenavir, ketoconazole/itraconazole)Reduced gastric acidity may lower absorption of these drugs and reduce their efficacy; see their labels.DailyMed (U.S. National Library of Medicine)

• Available data with H2-receptor antagonists including famotidine in pregnant women are insufficient to establish a drug-associated risk of major birth defects, miscarriage or adverse outcomes; no adverse developmental effects in animal studies at high multiples of the human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Limited data on famotidine in human milk; no effects on the breastfed infant reported. Weigh benefits of breastfeeding against maternal need.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Famotidine: Competitive inhibitor of histamine-2 receptors, inhibiting gastric acid secretion (US label 12.1).