سعر سيرفيبيب 20مجم 14 قرص 2022

Famotidine 20 mg film-coated tablets, pack of 14 (Servipep, Novartis, Egypt).

• Active duodenal ulcer and active gastric ulcerPopulation: Adults and paediatric patients 40 kg or moreDailyMed (U.S. National Library of Medicine)
• Symptomatic non-erosive GERD and erosive oesophagitis due to GERDPopulation: Adults and paediatric patients 40 kg or moreDailyMed (U.S. National Library of Medicine)
• Pathological hypersecretory conditions (e.g. Zollinger-Ellison syndrome, multiple endocrine neoplasias)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions: headache, dizziness, constipation and diarrhoea.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g. anaphylaxis) to famotidine or other H2-receptor antagonists.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CNS adverse reactions (confusion, delirium, hallucinations, disorientation, agitation, seizures, lethargy) have been reported in elderly patients and in moderate or severe renal impairment; reduce the dose in renal impairment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic response does not exclude gastric malignancy; consider evaluation before starting therapy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Drugs dependent on gastric pH for absorptionReduced gastric acidity may substantially lower systemic exposure and efficacy of the concomitant drug (see full US label list).DailyMed (U.S. National Library of Medicine)
• Tizanidine (CYP1A2 substrate)Potential substantial increase in tizanidine concentrations causing hypotension, bradycardia or excessive drowsiness; avoid concomitant use if possible.DailyMed (U.S. National Library of Medicine)

• Available data with H2-receptor antagonists, including famotidine, in pregnant women are insufficient to establish a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; no adverse developmental effects in animal studies at high multiples of the human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Limited data on famotidine in human milk, with no effects reported in breastfed infants; weigh the benefits of breastfeeding against the mother's clinical need and potential infant effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Famotidine: Competitive inhibitor of histamine-2 receptors that inhibits gastric acid secretion.