سعر نيزاتين 300مجم 20 كبسولة 2023

Nizatine 300 mg nizatidine capsules (Hi-Pharm, Egypt), box of 20; H2-receptor antagonist for peptic ulcer and GERD.

• Active duodenal ulcer (up to 8 weeks)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Maintenance therapy after healing of active duodenal ulcer (150 mg at bedtime)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Endoscopically diagnosed esophagitis including erosive and ulcerative esophagitis and associated heartburn due to GERD (up to 12 weeks)Population: AdultsDailyMed (U.S. National Library of Medicine)

• In placebo-controlled trials anaemia (0.2% vs 0%) and urticaria (0.5% vs 0.1%) were significantly more common; frequent events (similar to placebo) included headache, abdominal pain, diarrhoea, nausea, dizziness, rhinitis; rare hepatocellular injury, impotence, hyperuricaemia, eosinophilia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to nizatidine; history of hypersensitivity to other H2-receptor antagonists (cross-sensitivity).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not preclude gastric malignancy; reduce dosage in moderate to severe renal insufficiency (renally excreted); false-positive urobilinogen tests with Multistix may occur.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Aspirin (very high doses, 3.9 g/day)Increased serum salicylate levels when nizatidine 150 mg twice daily was given concurrently.DailyMed (U.S. National Library of Medicine)
• Theophylline, chlordiazepoxide, lorazepam, lidocaine, phenytoin, warfarinNo interactions observed; nizatidine does not inhibit cytochrome P450, so metabolic interactions are not expected.DailyMed (U.S. National Library of Medicine)

• Animal studies (rats, rabbits) showed no impaired fertility or fetal harm; no adequate studies in pregnant women; use in pregnancy only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• About 0.1% of an oral dose is secreted in human milk; growth depression in pups of treated lactating rats; decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Nizatidine: Competitive, reversible inhibitor of histamine at H2 receptors, particularly on gastric parietal cells, reducing gastric acid secretion; does not inhibit the cytochrome P450 system (US nizatidine labels).