سعر انتودين 40مجم 30 قرص 2024

Famotidine 40 mg film-coated tablets, 30 tablets (3 strips); H2-receptor antagonist for peptic ulcer and GERD.

• Active duodenal ulcer (DU) and active gastric ulcer (GU).Population: Adults and pediatric patients 40 kg and greaterDailyMed (U.S. National Library of Medicine)
• Symptomatic non-erosive gastroesophageal reflux disease (GERD) and erosive esophagitis due to GERD diagnosed by biopsy.Population: Adults and pediatric patients 40 kg and greaterDailyMed (U.S. National Library of Medicine)
• Pathological hypersecretory conditions (e.g. Zollinger-Ellison syndrome, multiple endocrine neoplasias).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (≥1%): headache, dizziness, constipation and diarrhea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g. anaphylaxis) to famotidine or other histamine-2 receptor antagonists.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Central nervous system adverse reactions (confusion, delirium, hallucinations, disorientation, agitation, seizures, lethargy) have been reported in elderly patients and patients with moderate-severe renal impairment; reduce the dose in renal impairment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic response to famotidine does not preclude the presence of gastric malignancy; consider evaluation in adults with a suboptimal response or early symptomatic relapse.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Drugs dependent on gastric pH for absorption (e.g. dasatinib, delavirdine, cefditoren, fosamprenavir, ketoconazole, itraconazole)Famotidine can reduce absorption and efficacy of these drugs; see their labeling; avoid or separate as recommended.DailyMed (U.S. National Library of Medicine)
• Tizanidine (CYP1A2 substrate)Famotidine, a weak CYP1A2 inhibitor, may increase tizanidine exposure leading to hypotension, bradycardia or excessive drowsiness; avoid concomitant use; if necessary monitor.DailyMed (U.S. National Library of Medicine)

• Available data with famotidine use in pregnant women are insufficient to establish a drug-associated risk of major birth defects, miscarriage or adverse outcomes; no adverse developmental effects in animal studies at doses far above the human dose.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Limited data show famotidine is present in human milk; no adverse effects on breastfed infants have been reported; consider the benefits of breastfeeding with the mother's clinical need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Famotidine: Competitive inhibitor of histamine-2 (H2) receptors; inhibits basal, nocturnal and stimulated gastric acid secretion (both acid concentration and volume).