سعر ابيجينت 3مجم/جم مرهم 2022

Apigent 3 mg/g eye/ear ointment (gentamicin), an aminoglycoside antibiotic ointment for ophthalmic and otic use by Amoun.

• Ocular bacterial infections: conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, dacryocystitisDailyMed (U.S. National Library of Medicine)

• Ocular burning and irritation on instillation, non-specific conjunctivitis, conjunctival epithelial defects and hyperaemia; bacterial/fungal corneal ulcers have developed during treatment; rarely allergic reactions, thrombocytopenic purpura and hallucinations.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to any of the components.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Perforated tympanic membrane (ear use), known allergy to gentamicin or other aminoglycosides, and myasthenia gravis and related conditions (UK SmPC for gentamicin eye/ear drops).General active-ingredient information · electronic medicines compendium (emc), UK

• Prolonged use may cause overgrowth of nonsusceptible organisms including fungi; bacterial resistance may develop; stop if purulent discharge, inflammation or pain worsens or if irritation/hypersensitivity occurs. Ophthalmic ointments may retard corneal healing.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Ear use: check the integrity of the ear drum before use; direct contact of gentamicin with the middle/inner ear may cause irreversible ototoxicity; increased ototoxicity risk with mitochondrial mutations (e.g. m.1555A>G).General active-ingredient information · electronic medicines compendium (emc), UK

• No adequate and well-controlled studies in pregnant women; systemic gentamicin in pregnant rats (about 500 times the maximum ophthalmic dose) depressed newborn body and kidney weights; use in pregnancy only if the benefit justifies the risk.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Safety in lactation has not been established; use only when considered essential (UK SmPC, eye/ear drops).General active-ingredient information · electronic medicines compendium (emc), UK

• Gentamicin: Bactericidal; its most important effect is inhibition of bacterial protein synthesis at the level of the 30S ribosomal subunit; also affects plasma-membrane integrity and RNA metabolism (UK SmPC, gentamicin eye/ear drops).