سعر اوبتيجينت 0.3% مرهم للعين والاذن 2024

Gentamicin 0.3% eye/ear ointment, 5 g tube.

• Topical treatment of ocular bacterial infections (conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, dacryocystitis) caused by susceptible organisms.DailyMed (NLM)

• Most frequent: ocular burning and irritation, non-specific conjunctivitis, conjunctival epithelial defects and hyperaemia; bacterial and fungal corneal ulcers have developed; rarely allergic reactions, thrombocytopenic purpura and hallucinations.International label, same formulation · DailyMed (NLM)

• Known hypersensitivity to any component.International label, same formulation · DailyMed (NLM)
• Allergy to gentamicin or other aminoglycosides; myasthenia gravis and related conditions; perforated tympanic membrane (otic use).International label, equivalent formulation · electronic medicines compendium (emc)

• Not for injection into the eye. Prolonged use may cause overgrowth of non-susceptible organisms including fungi; resistance may develop. Ophthalmic ointments may retard corneal healing.International label, same formulation · DailyMed (NLM)
• Ototoxicity risk with direct contact with the middle/inner ear: check ear-drum integrity before otic use; higher risk with mitochondrial mutations (m.1555A>G).International label, equivalent formulation · electronic medicines compendium (emc)

• Potent diuretics (ethacrynic acid, furosemide)Believed to enhance any risk of ototoxicity.electronic medicines compendium (emc)
• Curare-type muscle relaxantsNeuromuscular blockade and respiratory paralysis reported with aminoglycosides.electronic medicines compendium (emc)

• Systemic gentamicin at ~500 times the maximum ophthalmic dose depressed newborn body and kidney weights in rats; no adequate studies in pregnant women; use only if benefit justifies risk.International label, same formulation · DailyMed (NLM)
• Safety in lactation not established; use only when considered essential by the physician.International label, equivalent formulation · electronic medicines compendium (emc)

• Gentamicin: Bactericidal; mainly inhibits bacterial protein synthesis at the 30S ribosomal subunit and also affects plasma-membrane integrity and RNA metabolism.