سعر اواديسيبرو 500مجم 10 اقراص 2024

Ciprofloxacin 500 mg film-coated tablets (Awadicipro, HP Pharma, Egypt), a fluoroquinolone antibacterial; pack of 10 tablets (1 strip).

• Skin and skin structure infections.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Bone and joint infections.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Complicated intra-abdominal infections (in combination with metronidazole).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequently reported adverse reactions (all formulations): nausea (2.5%), diarrhoea (1.6%), abnormal liver function tests (1.3%), vomiting (1%) and rash (1%).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to ciprofloxacin, any member of the quinolone class or any product component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant administration with tizanidine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones have been associated with disabling and potentially irreversible serious adverse reactions occurring together, including tendinitis and tendon rupture, peripheral neuropathy and central nervous system effects; discontinue immediately and avoid fluoroquinolones in patients who experience them.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: may exacerbate muscle weakness in patients with myasthenia gravis; avoid in patients with a known history of myasthenia gravis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: because of these risks, reserve for patients with no alternative treatment options for acute exacerbation of chronic bronchitis, acute uncomplicated cystitis and acute sinusitis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• TizanidineContraindicated: potentiation of the hypotensive and sedative effects of tizanidine.DailyMed (U.S. National Library of Medicine)
• TheophyllineAvoid use: increased and prolonged theophylline exposure with serious and fatal reactions; if unavoidable, monitor serum theophylline and adjust the dose.DailyMed (U.S. National Library of Medicine)
• Drugs known to prolong the QT interval (e.g. class IA or III antiarrhythmics, tricyclic antidepressants, macrolides, antipsychotics)Avoid use: ciprofloxacin may further prolong the QT interval.DailyMed (U.S. National Library of Medicine)

• Prolonged experience with ciprofloxacin in pregnant women over several decades (case reports, case-control and observational studies) has not identified any drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Ciprofloxacin is present in human milk; because of potential serious adverse reactions in breastfed infants (including arthropathy in juvenile animals), a woman may pump and discard milk during treatment and for 2 more days after the last dose, or not breastfeed during that time.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ciprofloxacin: Bactericidal fluoroquinolone that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes required for DNA replication, transcription, repair and recombination.