سعر كيموتريم 400/80مجم 20 قرص 2023

Chemotrim 400/80mg 20 tabs: Sulfamethoxazole + trimethoprim (Kahira).

• Treatment of urinary tract infections and other susceptible bacterial infections per co-trimoxazole labeling (US).DailyMed (NLM)

• Known sulfonamide or trimethoprim hypersensitivity; megaloblastic anemia due to folate deficiency; marked hepatic damage; severe renal insufficiency when status cannot be monitored; infants <2 months (systemic).General active-ingredient information · DailyMed (NLM)

• Fatalities from severe reactions (SJS/TEN, fulminant hepatic necrosis, agranulocytosis) reported with sulfonamides; C. difficile-associated diarrhea; hyperkalemia (trimethoprim); photosensitivity.General active-ingredient information · DailyMed (NLM)

• WarfarinMajorMay potentiate hypoprothrombinemic effect — monitor INR.DailyMed (NLM)
• ACE inhibitors / spironolactoneMajorTrimethoprim may cause hyperkalemia — monitor potassium.DailyMed (NLM)

• Use in pregnancy only if potential benefit justifies potential risk; sulfonamides may cause kernicterus near term; trimethoprim is a folate antagonist.General active-ingredient information · DailyMed (NLM)

• Sulfamethoxazole: Competes with PABA to inhibit dihydropteroate synthase in folate synthesis.
• Trimethoprim: Inhibits bacterial dihydrofolate reductase, blocking tetrahydrofolate production.