سعر كليناسين300 مجم كبسولات 2022

Clinacyn 300mg 16 caps.: clindamycin 300 mg capsules (Sigma > egyptian pharmacists company).

• Oral lincosamide antibacterial for serious susceptible infections (anaerobic and selected gram-positive), reserved for serious infections where less toxic agents are inappropriate; not for most nonbacterial upper respiratory infections (US Cleocin HCl).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Contraindicated in hypersensitivity to clindamycin or lincomycin (US Cleocin HCl label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: Clostridioides difficile infection (CDI) reported with nearly all antibacterials including clindamycin and may range from mild diarrhea to fatal colitis; reserve for serious infections; discontinue if significant diarrhea occurs (US Cleocin HCl).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Neuromuscular blocking agentsModerateClindamycin may enhance neuromuscular blockade (US Cleocin HCl).DailyMed (U.S. National Library of Medicine)
• Strong CYP3A4 inhibitors/inducersClindamycin is a CYP3A4/3A5 substrate; strong inhibitors may raise levels and inducers may lower efficacy (US Cleocin HCl).DailyMed (U.S. National Library of Medicine)

• US Cleocin HCl label: systemic use in 2nd/3rd trimester not associated with increased congenital abnormalities in available data; use in 1st trimester only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Present in breast milk (<0.5–3.8 mcg/mL); breastfeeding not recommended during oral clindamycin or monitor infant for GI effects (US Cleocin HCl label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Clindamycin: Binds the 23S rRNA of the bacterial 50S ribosomal subunit and inhibits protein synthesis; bacteriostatic (US Cleocin HCl label).