سعر كوبريماسبت معلق 100 مل 2022

Coprimasept oral susp. 100 ml: Sulphamethoxazole + Trimethoprim (Pharopharma).

• Co-trimoxazole (SMX/TMP) is used for susceptible bacterial infections including certain urinary tract infections, acute exacerbations of chronic bronchitis, and Pneumocystis jirovecii pneumonia (prevention/treatment) per labeling — confirm Coprimasept Egyptian indications.Population: Patients with labeled susceptible infectionsDailyMed (U.S. National Library of Medicine)

• Common: nausea, vomiting, anorexia, rash; serious: Stevens-Johnson syndrome, agranulocytosis, hepatitis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to sulfonamides or trimethoprim; megaloblastic anemia due to folate deficiency; generally contraindicated in marked hepatic damage and severe renal insufficiency as labeled.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Serious skin reactions (SJS/TEN), blood dyscrasias, hepatic necrosis, hyperkalemia possible; increased risk in elderly and with folate deficiency; counsel on hydration and sun sensitivity.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• WarfarinMajorSMX/TMP may increase anticoagulant effect of warfarin — monitor INR.DailyMed (U.S. National Library of Medicine)
• MethotrexateMajorMay increase methotrexate toxicity via competition for renal secretion / folate pathway effects.DailyMed (U.S. National Library of Medicine)

• Sulfonamides may cause kernicterus in neonates; trimethoprim is a folate antagonist — use in pregnancy only if benefits outweigh risks per current labeling; confirm Egyptian leaflet.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Sulfamethoxazole: Competes with PABA to inhibit dihydropteroate synthase in folate synthesis.
• Trimethoprim: Inhibits bacterial dihydrofolate reductase, blocking tetrahydrofolate production.