سعر كوزارنوميد 600 مجم 10 قرص 2022

Cosarnomid 600 mg 10 f.c. tab.: Eprosartan (Pharmed healthcare).

• Essential hypertension (UK Teveten 600 mg SmPC).Population: Adultselectronic Medicines Compendium (eMC) / MHRA

• Most common: headache (~11%) and nonspecific GI complaints (~8%); dizziness, rhinitis, allergic skin reactions, asthenia (UK Teveten).International label, same formulation · electronic Medicines Compendium (eMC) / MHRA

• Hypersensitivity; second and third trimester of pregnancy; severe hepatic impairment; haemodynamically significant bilateral renovascular disease or severe stenosis of a solitary functioning kidney; concomitant aliskiren in diabetes or renal impairment GFR <60 (UK Teveten).International label, same formulation · electronic Medicines Compendium (eMC) / MHRA

• Correct volume/sodium depletion before starting; caution in renal impairment and dual RAAS blockade; monitor potassium; intestinal angioedema reported with ARBs (UK Teveten).International label, same formulation · electronic Medicines Compendium (eMC) / MHRA

• Aliskiren / ACE inhibitors (dual RAAS blockade)MajorConcomitant use with aliskiren contraindicated in diabetes or GFR <60; dual RAAS blockade increases hypotension, hyperkalaemia and renal failure risk (UK Teveten).electronic Medicines Compendium (eMC) / MHRA
• NSAIDsModerateMay worsen renal function and blunt antihypertensive effect; hydrate and monitor renal function (UK Teveten).electronic Medicines Compendium (eMC) / MHRA

• ARBs contraindicated in 2nd/3rd trimester; not recommended in 1st trimester; known foetotoxicity with 2nd/3rd trimester exposure (UK Teveten).International label, same formulation · electronic Medicines Compendium (eMC) / MHRA
• Not recommended during breast-feeding; prefer alternatives with better established lactation safety (UK Teveten).International label, same formulation · electronic Medicines Compendium (eMC) / MHRA

• Eprosartan: Selective AT1 antagonist; blocks angiotensin II vasoconstriction and aldosterone secretion.