سعر كوفرسيل 5 مجم 30 قرص 2024

Coversyl 5 mg film-coated tablets, 30 per pack (Servier, Egypt).

• Treatment of hypertension; treatment of symptomatic heart failure; reduction of risk of cardiac events in patients with history of myocardial infarction and/or revascularisation (stable CAD).Population: AdultsMHRA / eMC

• Common: headache, dizziness, vertigo, paraesthesia, visual disturbance, tinnitus, hypotension, cough, dyspnoea, abdominal pain, diarrhoea, constipation, nausea, dyspepsia, rash, pruritus, muscle cramps, asthenia.International label, same formulation · MHRA / eMC

• Hypersensitivity to perindopril or other ACE inhibitors/excipients; history of ACE-inhibitor angioedema; hereditary/idiopathic angioedema; 2nd/3rd trimester pregnancy; concomitant aliskiren in diabetes or renal impairment; sacubitril/valsartan within 36 h; extracorporeal treatments with negatively charged membranes; significant bilateral renal-artery stenosis.International label, same formulation · MHRA / eMC

• Angioedema risk; monitor BP, creatinine and potassium; dual RAAS blockade not recommended; hyperkalaemia; dry cough; caution in volume depletion, renovascular disease, collagen disease, hepatic failure; less BP effect in Black patients.International label, same formulation · MHRA / eMC

• Potassium-sparing diuretics / aliskiren / ARBsMajorIncreased hyperkalaemia and renal risk; avoid dual blockade.MHRA / eMC
• NSAIDsModerateMay reduce antihypertensive effect and impair renal function.MHRA / eMC
• LithiumMajorRisk of lithium toxicity; avoid or monitor levels.MHRA / eMC

• ACE inhibitors contraindicated in 2nd/3rd trimester; not recommended in 1st trimester or lactation.International label, same formulation · MHRA / eMC

• Perindopril (as perindopril arginine): Inhibits angiotensin-converting enzyme, reducing conversion of angiotensin I to the vasoconstrictor angiotensin II and the degradation of bradykinin.