سعر سيكلوبروجينوفا 21 قرص 2025

Cyclo-progynova 21 f.c. tab. (biphasic): Estradiol valerate + norgestrel (Bayer schering > bayer healthcare).

• Hormone replacement therapy for estrogen-deficiency symptoms in perimenopausal and postmenopausal women; prevention of osteoporosis in postmenopausal women at high risk when other treatments unsuitable (Bayer Cyclo-Progynova SmPC / sequential estradiol valerate + norgestrel).Population: Perimenopausal/postmenopausal women with intact uterusBayer

• Breast tenderness/pain, headache, nausea, uterine/vaginal bleeding including spotting, abdominal pain, mood changes, edema (HRT / Cyclo-Progynova class effects).International label, same product · Bayer

• Known/suspected breast cancer or other estrogen-dependent malignancy; undiagnosed genital bleeding; untreated endometrial hyperplasia; previous/current VTE; known thrombophilic disorders; active/recent arterial thromboembolic disease; acute liver disease or unresolved liver function tests; porphyria; hypersensitivity (HRT class / Cyclo-Progynova SmPC).International label, same product · Bayer

• HRT risks include breast cancer, VTE, stroke, CHD in some populations; use lowest effective dose for shortest duration; regular medical review; not a contraceptive (Bayer Cyclo-Progynova SmPC).International label, same product · Bayer

• Not indicated during pregnancy; discontinue if pregnancy occurs (Cyclo-Progynova SmPC).International label, same product · Bayer
• Not indicated during lactation (Cyclo-Progynova SmPC).International label, same product · Bayer

• Estradiol valerate: Estradiol valerate is hydrolyzed to estradiol, which binds estrogen receptors mediating genomic effects on genital tract, bone, and other estrogen-responsive tissues.
• Norgestrel: Binds progesterone receptors; in sequential HRT opposes estrogenic stimulation of the endometrium.