سعر ديكاديل 200 مجم/5 مل محلول فموي 125 مل 2024

Dekadel 200mg/5ml oral solution 125 ml: Sodium valproate (Delta Pharma).

• Boxed warning (US valproate products): hepatotoxicity, fetal risk (neural tube defects / decreased IQ), and pancreatitis. Contraindicated in pregnancy for migraine prophylaxis; use effective contraception.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Carbapenems (e.g. meropenem)MajorCarbapenems may reduce valproate levels and cause loss of seizure control (US labeling).DailyMed (U.S. National Library of Medicine)

• Valproate can cause major congenital malformations and decreased IQ after in utero exposure; contraindicated for migraine prophylaxis in pregnant women; for epilepsy use only if other treatments ineffective (US labeling).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Sodium valproate: Increases GABA availability and modulates neuronal excitability; exact mechanism multifactorial.