سعر بالينوزار 150 مجم 20 كبسولة 2022

Pregabalin 150 mg hard capsules, pack of 20; gabapentinoid anti-epileptic and neuropathic pain agent (Pharma Cure Pharmaceuticals, Egypt).

• Neuropathic pain associated with diabetic peripheral neuropathyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Postherpetic neuralgiaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizuresPopulation: Patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions: dizziness, somnolence, dry mouth, oedema, blurred vision, weight gain and thinking abnormal (primarily difficulty with concentration/attention).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any of its components.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema (swelling of face, mouth, lips, throat) has been reported, sometimes life-threatening; discontinue immediately; use caution in patients with a history of angioedema or taking other drugs associated with angioedema (e.g., ACE inhibitors).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity reactions (skin redness, blisters, hives, rash, dyspnoea, wheezing); discontinue immediately if they occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs increase the risk of suicidal thoughts or behaviour; monitor for emergence or worsening of depression, suicidal thoughts or unusual changes in mood or behaviour.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids and other CNS depressants (e.g., benzodiazepines, alcohol)Additive CNS depression; increased risk of respiratory depression, somnolence and cognitive/motor impairment.DailyMed (U.S. National Library of Medicine)
• ACE inhibitorsPossible increased risk of angioedema with concomitant use.DailyMed (U.S. National Library of Medicine)
• Thiazolidinedione antidiabetics (e.g., pioglitazone, rosiglitazone)Additive peripheral oedema and weight gain; use caution.DailyMed (U.S. National Library of Medicine)

• Observational data suggest a possible small increase in the rate of major birth defects with pregabalin exposure in pregnancy; animal studies showed developmental toxicity. Neonatal withdrawal symptoms have been reported when pregabalin was used with opioids near delivery. A pregnancy registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pregabalin is present in human milk (about 76% of maternal plasma concentrations; estimated infant dose about 7% of the maternal dose); because of the tumorigenicity observed in animal studies, breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues; the exact mechanism of its analgesic and anticonvulsant effects is unknown.