سعر ابيفال 10 مجم /2مل 3 امبولات 2024

Diazepam 10 mg/2 ml solution for IM/IV injection or IV infusion, 3 ampoules (EIPICO Epival).

• Directory: treatment of epilepsy; reduction of seizures associated with epilepsy
• Management of anxiety disorders or short-term relief of symptoms of anxiety.DailyMed (U.S. NLM)
• Acute alcohol withdrawal: symptomatic relief of acute agitation, tremor, impending or acute delirium tremens and hallucinosis.Population: AdultsDailyMed (U.S. NLM)

• Most common: drowsiness, fatigue and ataxia; venous thrombosis and phlebitis at the injection site. Less often: confusion, respiratory depression, hypotension, bradycardia, cardiovascular collapse, blurred vision, urticaria; paradoxical reactions.International label, equivalent formulation · DailyMed (U.S. NLM)

• Known hypersensitivity to diazepam; acute narrow-angle glaucoma; open-angle glaucoma unless the patient is receiving appropriate therapy.International label, equivalent formulation · DailyMed (U.S. NLM)

• Boxed warning: concomitant use of benzodiazepines and opioids may cause profound sedation, respiratory depression, coma and death; reserve co-prescribing for patients without alternatives and limit dose and duration.International label, equivalent formulation · DailyMed (U.S. NLM)
• Boxed warning: benzodiazepines carry risks of abuse, misuse and addiction that can lead to overdose or death; assess each patient's risk before and during treatment.International label, equivalent formulation · DailyMed (U.S. NLM)
• Boxed warning: continued use may cause clinically significant physical dependence; abrupt discontinuation or rapid dose reduction may precipitate life-threatening withdrawal reactions, so taper gradually.International label, equivalent formulation · DailyMed (U.S. NLM)

• OpioidsAdditive respiratory depression and sedation; limit dose and duration of concomitant use and monitor closely.DailyMed (U.S. NLM)
• Alcohol and other CNS depressants (phenothiazines, antipsychotics, hypnotics, barbiturates, MAO inhibitors and other antidepressants)Potentiation of CNS depressant effects; concomitant alcohol is not recommended.DailyMed (U.S. NLM)
• Inhibitors of CYP3A and CYP2C19 (e.g., cimetidine, ketoconazole, fluvoxamine, fluoxetine, omeprazole)May increase and prolong diazepam sedation.DailyMed (U.S. NLM)

• Diazepam is present in breast milk; sedation, poor feeding and poor weight gain have been reported in exposed infants. Breastfeeding is not recommended during treatment.International label, equivalent formulation · DailyMed (U.S. NLM)

• Diazepam: Benzodiazepine derivative acting at GABA-A receptor sites in the CNS (US diazepam labeling).