سعر فينوليب 100 مجم 10 كبسولات 2022

Fenolip 100 mg capsules (fenofibrate), pack of 10, by Alfacure Pharmaceuticals; a fibrate lipid-lowering medicine.

• Muscle effects (myalgia, tenderness, weakness, rare rhabdomyolysis); dyspepsia and other digestive disorders; raised transaminases; gallstones; rash, pruritus, urticaria or photosensitivity; very rarely interstitial pneumopathy.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Hepatic insufficiency; renal insufficiency; hypersensitivity to fenofibrate or excipients; known phototoxic or photoallergic reactions to fibrates or structurally related substances, especially ketoprofen; children.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Muscle toxicity including rare rhabdomyolysis (higher risk with hypoalbuminaemia, age over 70, renal impairment, hypothyroidism, alcohol, or combination with statins or other fibrates); transient transaminase rises; pancreatitis reported; reinforce INR monitoring with oral anticoagulants; check for secondary hyperlipidaemia in women on oestrogens; consider other therapy if lipids are not adequately reduced after 3-6 months.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• HMG-CoA reductase inhibitors (statins) and other fibratesIncreased risk of serious muscle toxicity; use with caution and close monitoring.ANSM (Agence nationale de sécurité du médicament), France
• Oral anticoagulantsEnhanced anticoagulant effect and bleeding risk; monitor INR and reduce the anticoagulant dose by about one third during treatment and for 8 days after stopping.ANSM (Agence nationale de sécurité du médicament), France
• CiclosporinRisk of increased ciclosporin nephrotoxicity; monitor renal function.ANSM (Agence nationale de sécurité du médicament), France

• No teratogenic effect in animals and none observed clinically to date, but data are insufficient; fibrates are not indicated in pregnancy except for major hypertriglyceridaemia (>10 g/L) inadequately corrected by diet with maternal pancreatitis risk.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France
• No information on passage into breast milk; prescription during breastfeeding is not advised.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Transaminases every 3 months during the first 12 months; stop if ALT/AST exceed 3 times the upper limit of normal; check CK if muscle symptoms occur; periodic lipid assessment.General active-ingredient information · ANSM (Agence nationale de sécurité du médicament), France

• Fenofibrate: Prodrug hydrolysed to fenofibric acid, which activates PPAR-alpha, increasing lipoprotein lipase activity and lowering triglycerides and LDL cholesterol.